Abstract P-17: Structural and Functional Insights into Eukaryotic Translation Reinitiation and Ribosome Recycling Orchestrated by eIF2D and MCT-1/DENR

Abstract P-17: Structural and Functional Insights into Eukaryotic Translation Reinitiation and Ribosome Recycling Orchestrated by eIF2D and MCT-1/DENR

The last stage of translation cycle is ribosome recycling which occurs after completed polypeptide is released. This step comprises dissociation of 60S ribosomal subunit, followed by tRNA and mRNA removal from the 40S-tRNA-mRNA post-termination complex. However, in some cases unrecycled 40S subunit...

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Bibliographic Details
Main Authors: Desislava S. Makeeva, Elena A. Stolboushkina, Ivan B. Lomakin, Sergey E. Dmitriev
Format: Article
Language:English
Published: International Medical Research and Development Corporation 2019-06-01
Series:International Journal of Biomedicine
Subjects:
protein synthesis
translation reinitiation and ribosome recycling
eIF2D/ligatin
MCTS1
Online Access:http://ijbm.org/articles/IJBM_2019_9_S1_P17.pdf

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