Recent Advances in Substrate-Controlled Asymmetric Cyclization for Natural Product Synthesis

Asymmetric synthesis of naturally occurring diverse ring systems is an ongoing and challenging research topic. A large variety of remarkable reactions utilizing chiral substrates, auxiliaries, reagents, and catalysts have been intensively investigated. This review specifically describes recent advan...

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Main Authors: Jeyun Jo, Seok-Ho Kim, Young Taek Han, Jae-Hwan Kwak, Hwayoung Yun
Format: Article
Language:English
Published: MDPI AG 2017-06-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/22/7/1069
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author Jeyun Jo
Seok-Ho Kim
Young Taek Han
Jae-Hwan Kwak
Hwayoung Yun
author_facet Jeyun Jo
Seok-Ho Kim
Young Taek Han
Jae-Hwan Kwak
Hwayoung Yun
author_sort Jeyun Jo
collection DOAJ
description Asymmetric synthesis of naturally occurring diverse ring systems is an ongoing and challenging research topic. A large variety of remarkable reactions utilizing chiral substrates, auxiliaries, reagents, and catalysts have been intensively investigated. This review specifically describes recent advances in successful asymmetric cyclization reactions to generate cyclic architectures of various natural products in a substrate-controlled manner.
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spelling doaj.art-1725cca094284ac2b13448a7c63812602022-12-22T03:20:08ZengMDPI AGMolecules1420-30492017-06-01227106910.3390/molecules22071069molecules22071069Recent Advances in Substrate-Controlled Asymmetric Cyclization for Natural Product SynthesisJeyun Jo0Seok-Ho Kim1Young Taek Han2Jae-Hwan Kwak3Hwayoung Yun4College of Pharmacy, Pusan National University, Busan 46241, KoreaCollege of Pharmacy, Institute of Pharmaceutical Sciences, Cha University, Pocheon-si 11160, KoreaCollege of Pharmacy, Dankook University, Cheonan 31116, KoreaCollege of Pharmacy, Kyungsung University, Busan 48434, KoreaCollege of Pharmacy, Pusan National University, Busan 46241, KoreaAsymmetric synthesis of naturally occurring diverse ring systems is an ongoing and challenging research topic. A large variety of remarkable reactions utilizing chiral substrates, auxiliaries, reagents, and catalysts have been intensively investigated. This review specifically describes recent advances in successful asymmetric cyclization reactions to generate cyclic architectures of various natural products in a substrate-controlled manner.http://www.mdpi.com/1420-3049/22/7/1069asymmetric cyclizationsubstrate-controlled mannertotal synthesisnatural product
spellingShingle Jeyun Jo
Seok-Ho Kim
Young Taek Han
Jae-Hwan Kwak
Hwayoung Yun
Recent Advances in Substrate-Controlled Asymmetric Cyclization for Natural Product Synthesis
Molecules
asymmetric cyclization
substrate-controlled manner
total synthesis
natural product
title Recent Advances in Substrate-Controlled Asymmetric Cyclization for Natural Product Synthesis
title_full Recent Advances in Substrate-Controlled Asymmetric Cyclization for Natural Product Synthesis
title_fullStr Recent Advances in Substrate-Controlled Asymmetric Cyclization for Natural Product Synthesis
title_full_unstemmed Recent Advances in Substrate-Controlled Asymmetric Cyclization for Natural Product Synthesis
title_short Recent Advances in Substrate-Controlled Asymmetric Cyclization for Natural Product Synthesis
title_sort recent advances in substrate controlled asymmetric cyclization for natural product synthesis
topic asymmetric cyclization
substrate-controlled manner
total synthesis
natural product
url http://www.mdpi.com/1420-3049/22/7/1069
work_keys_str_mv AT jeyunjo recentadvancesinsubstratecontrolledasymmetriccyclizationfornaturalproductsynthesis
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AT youngtaekhan recentadvancesinsubstratecontrolledasymmetriccyclizationfornaturalproductsynthesis
AT jaehwankwak recentadvancesinsubstratecontrolledasymmetriccyclizationfornaturalproductsynthesis
AT hwayoungyun recentadvancesinsubstratecontrolledasymmetriccyclizationfornaturalproductsynthesis