Activation of Notch1 signaling in podocytes by glucose-derived AGEs contributes to proteinuria

Activation of Notch1 signaling in podocytes by glucose-derived AGEs contributes to proteinuria

Introduction Advanced glycation end-products (AGEs) are implicated in the pathogenesis of diabetic nephropathy (DN). Previous studies have shown that AGEs contribute to glomerulosclerosis and proteinuria. Podocytes, terminally differentiated epithelial cells of the glomerulus and the critical compon...

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Bibliographic Details
Main Authors:	Rajkishor Nishad, Prajakta Meshram, Ashish Kumar Singh, G Bhanuprakash Reddy, Anil Kumar Pasupulati
Format:	Article
Language:	English
Published:	BMJ Publishing Group 2020-04-01
Series:	BMJ Open Diabetes Research & Care
Online Access:	https://drc.bmj.com/content/8/1/e001203.full

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