Global impact of varicella vaccination programs
Although varicella is usually a mild and self-limited disease, complications can occur. In 1998, the World Health Organization recommended varicella vaccination for countries where the disease has a significant public health burden. Nonetheless, concerns about a shift in the disease to older groups,...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2019-03-01
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| Series: | Human Vaccines & Immunotherapeutics |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/21645515.2018.1546525 |
| _version_ | 1797677389475479552 |
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| author | Fernanda Hammes Varela Leonardo Araújo Pinto Marcelo Comerlato Scotta |
| author_facet | Fernanda Hammes Varela Leonardo Araújo Pinto Marcelo Comerlato Scotta |
| author_sort | Fernanda Hammes Varela |
| collection | DOAJ |
| description | Although varicella is usually a mild and self-limited disease, complications can occur. In 1998, the World Health Organization recommended varicella vaccination for countries where the disease has a significant public health burden. Nonetheless, concerns about a shift in the disease to older groups, an increase in herpes zoster in the elderly and cost-effectiveness led many countries to postpone universal varicella vaccine introduction. In this review, we summarize the accumulating evidence, available mostly from high and middle-income countries supporting a high impact of universal vaccination in reductions of the incidence of the disease and hospitalizations and its cost-effectiveness. We have also observed the effect of herd immunity and noted that there is no definitive and consistent association between vaccination and the increase in herpes zoster incidence in the elderly. |
| first_indexed | 2024-03-11T22:44:23Z |
| format | Article |
| id | doaj.art-173304695497480d9c449c7168c7e192 |
| institution | Directory Open Access Journal |
| issn | 2164-5515 2164-554X |
| language | English |
| last_indexed | 2024-03-11T22:44:23Z |
| publishDate | 2019-03-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj.art-173304695497480d9c449c7168c7e1922023-09-22T08:38:24ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2019-03-0115364565710.1080/21645515.2018.15465251546525Global impact of varicella vaccination programsFernanda Hammes Varela0Leonardo Araújo Pinto1Marcelo Comerlato Scotta2School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)Although varicella is usually a mild and self-limited disease, complications can occur. In 1998, the World Health Organization recommended varicella vaccination for countries where the disease has a significant public health burden. Nonetheless, concerns about a shift in the disease to older groups, an increase in herpes zoster in the elderly and cost-effectiveness led many countries to postpone universal varicella vaccine introduction. In this review, we summarize the accumulating evidence, available mostly from high and middle-income countries supporting a high impact of universal vaccination in reductions of the incidence of the disease and hospitalizations and its cost-effectiveness. We have also observed the effect of herd immunity and noted that there is no definitive and consistent association between vaccination and the increase in herpes zoster incidence in the elderly.http://dx.doi.org/10.1080/21645515.2018.1546525chickenpoxvaricella zoster viruschickenpox vaccineimmunization programsherpes zoster |
| spellingShingle | Fernanda Hammes Varela Leonardo Araújo Pinto Marcelo Comerlato Scotta Global impact of varicella vaccination programs Human Vaccines & Immunotherapeutics chickenpox varicella zoster virus chickenpox vaccine immunization programs herpes zoster |
| title | Global impact of varicella vaccination programs |
| title_full | Global impact of varicella vaccination programs |
| title_fullStr | Global impact of varicella vaccination programs |
| title_full_unstemmed | Global impact of varicella vaccination programs |
| title_short | Global impact of varicella vaccination programs |
| title_sort | global impact of varicella vaccination programs |
| topic | chickenpox varicella zoster virus chickenpox vaccine immunization programs herpes zoster |
| url | http://dx.doi.org/10.1080/21645515.2018.1546525 |
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