Effect of interferon on the development of Trypanosoma cruzi in tissue culture "Vero" cells

Results are presented on the effects of interferon on the intracellular stages of T. cruzi in tissue culture "Vero" cells. Interferon was obtained by infecting monolayers of human amniotic cells with inactivated Newcastle disease virus. Interferon has not affected the cell infection by T....

Full description

Bibliographic Details
Main Authors: R. R. Golgher, M. S. M. Bertelli, M. L. Petrillo-Peixoto, Z. Brener
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 1980-01-01
Series:Memorias do Instituto Oswaldo Cruz
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761980000100015
_version_ 1797758418958680064
author R. R. Golgher
M. S. M. Bertelli
M. L. Petrillo-Peixoto
Z. Brener
author_facet R. R. Golgher
M. S. M. Bertelli
M. L. Petrillo-Peixoto
Z. Brener
author_sort R. R. Golgher
collection DOAJ
description Results are presented on the effects of interferon on the intracellular stages of T. cruzi in tissue culture "Vero" cells. Interferon was obtained by infecting monolayers of human amniotic cells with inactivated Newcastle disease virus. Interferon has not affected the cell infection by T. cruzi culture infective stages and neither has it prevented the transformation of amastigote into trypomastigote stages.<br>Interferon obtido através da infecção de células amnióticas humanas por vírus inativado da doença de Newcastle foi incapaz de influir sobre a infectividade de formas de cultura do T. cruzi para células "Vero" de cultura de tecido. A transformação amastigota-tripomastigota também não foi afetada pelo interferon.
first_indexed 2024-03-12T18:29:42Z
format Article
id doaj.art-173454cb278445f7a0abecddf4720f94
institution Directory Open Access Journal
issn 0074-0276
1678-8060
language English
last_indexed 2024-03-12T18:29:42Z
publishDate 1980-01-01
publisher Fundação Oswaldo Cruz (FIOCRUZ)
record_format Article
series Memorias do Instituto Oswaldo Cruz
spelling doaj.art-173454cb278445f7a0abecddf4720f942023-08-02T08:19:27ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80601980-01-01751-215716010.1590/S0074-02761980000100015Effect of interferon on the development of Trypanosoma cruzi in tissue culture "Vero" cellsR. R. GolgherM. S. M. BertelliM. L. Petrillo-PeixotoZ. BrenerResults are presented on the effects of interferon on the intracellular stages of T. cruzi in tissue culture "Vero" cells. Interferon was obtained by infecting monolayers of human amniotic cells with inactivated Newcastle disease virus. Interferon has not affected the cell infection by T. cruzi culture infective stages and neither has it prevented the transformation of amastigote into trypomastigote stages.<br>Interferon obtido através da infecção de células amnióticas humanas por vírus inativado da doença de Newcastle foi incapaz de influir sobre a infectividade de formas de cultura do T. cruzi para células "Vero" de cultura de tecido. A transformação amastigota-tripomastigota também não foi afetada pelo interferon.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761980000100015
spellingShingle R. R. Golgher
M. S. M. Bertelli
M. L. Petrillo-Peixoto
Z. Brener
Effect of interferon on the development of Trypanosoma cruzi in tissue culture "Vero" cells
Memorias do Instituto Oswaldo Cruz
title Effect of interferon on the development of Trypanosoma cruzi in tissue culture "Vero" cells
title_full Effect of interferon on the development of Trypanosoma cruzi in tissue culture "Vero" cells
title_fullStr Effect of interferon on the development of Trypanosoma cruzi in tissue culture "Vero" cells
title_full_unstemmed Effect of interferon on the development of Trypanosoma cruzi in tissue culture "Vero" cells
title_short Effect of interferon on the development of Trypanosoma cruzi in tissue culture "Vero" cells
title_sort effect of interferon on the development of trypanosoma cruzi in tissue culture vero cells
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761980000100015
work_keys_str_mv AT rrgolgher effectofinterferononthedevelopmentoftrypanosomacruziintissuecultureverocells
AT msmbertelli effectofinterferononthedevelopmentoftrypanosomacruziintissuecultureverocells
AT mlpetrillopeixoto effectofinterferononthedevelopmentoftrypanosomacruziintissuecultureverocells
AT zbrener effectofinterferononthedevelopmentoftrypanosomacruziintissuecultureverocells