Proneurotrophin-3 promotes cell cycle withdrawal of developing cerebellar granule cell progenitors via the p75 neurotrophin receptor

Proneurotrophin-3 promotes cell cycle withdrawal of developing cerebellar granule cell progenitors via the p75 neurotrophin receptor

Cerebellar granule cell progenitors (GCP) proliferate extensively in the external granule layer (EGL) of the developing cerebellum prior to differentiating and migrating. Mechanisms that regulate the appropriate timing of cell cycle withdrawal of these neuronal progenitors during brain development a...

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Bibliographic Details
Main Authors: Juan Pablo Zanin, Elizabeth Abercrombie, Wilma J Friedman
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-07-01
Series:eLife
Subjects:
neurotrophins
cell proliferation
p75 neurotrophin receptor
cerebellum development
HDAC1
proNT3
Online Access:https://elifesciences.org/articles/16654

Internet

https://elifesciences.org/articles/16654

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