Motor performance after treatment of pilocytic astrocytoma in the posterior fossa in childhood
Abstract Background Pilocytic astrocytoma is the most common brain tumour type in childhood located in the posterior fossa, and treated mainly with surgery. These tumours have low mortality, but knowledge concerning its long‐term outcome is sparse. Aims The aim was to investigate if patients treated...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-08-01
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| Series: | Cancer Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/cnr2.1548 |
| _version_ | 1811221195932041216 |
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| author | Ingela Kristiansen Gunilla E. Frykberg Anette Höglund Annette Sondell Bo Strömberg Per Frisk |
| author_facet | Ingela Kristiansen Gunilla E. Frykberg Anette Höglund Annette Sondell Bo Strömberg Per Frisk |
| author_sort | Ingela Kristiansen |
| collection | DOAJ |
| description | Abstract Background Pilocytic astrocytoma is the most common brain tumour type in childhood located in the posterior fossa, and treated mainly with surgery. These tumours have low mortality, but knowledge concerning its long‐term outcome is sparse. Aims The aim was to investigate if patients treated for pilocytic astrocytoma in the posterior fossa had motor complications, including balance, motor and process skills. Methods and Results This descriptive single‐centre study includes eight children and 12 adults, treated for pilocytic astrocytoma as children. Motor performance was investigated with Bruininks–Oseretsky Test of Motor Proficiency, Second Edition, and dynamic balance with the mini‐balance evaluation systems test. Physiological cost index, six‐minute walk test, hand grip strength and assessment of motor and process skills were also evaluated. Ten patients reported motor difficulties, mainly from the upper limbs. The motor performance test showed results within normal limits except for manual dexterity, which was significantly below mean (p = .008). In the dynamic balance test patients had significantly lower results compared with controls (p = .036). Physiological cost index, six‐minute walk tests and hand grip strength showed results within normal limits. In the Assessment of Motor and Process Skills, patients over 16 years had significantly lower results compared with test norms for motor activities of daily living (ADL) and 30% of all patients scored below the cut‐off level for difficulties with motor skills. Conclusions Motor performance for patients treated for pilocytic astrocytoma in the posterior fossa in childhood is satisfactory but some patients display difficulties with balance, manual dexterity and ADL motor skills. Thus, it is important to identify those in need of motor follow‐up and training. |
| first_indexed | 2024-04-12T07:55:09Z |
| format | Article |
| id | doaj.art-173b4d0e8621453089a100a6fc1a32c6 |
| institution | Directory Open Access Journal |
| issn | 2573-8348 |
| language | English |
| last_indexed | 2024-04-12T07:55:09Z |
| publishDate | 2022-08-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cancer Reports |
| spelling | doaj.art-173b4d0e8621453089a100a6fc1a32c62022-12-22T03:41:30ZengWileyCancer Reports2573-83482022-08-0158n/an/a10.1002/cnr2.1548Motor performance after treatment of pilocytic astrocytoma in the posterior fossa in childhoodIngela Kristiansen0Gunilla E. Frykberg1Anette Höglund2Annette Sondell3Bo Strömberg4Per Frisk5Department of Women's and Children's Health Uppsala University and Uppsala University Children's Hospital Uppsala SwedenDepartment of Neuroscience/Rehabilitation Medicine Uppsala University Uppsala SwedenDepartment of Women's and Children's Health Uppsala University and Uppsala University Children's Hospital Uppsala SwedenDepartment of Women's and Children's Health Uppsala University and Uppsala University Children's Hospital Uppsala SwedenDepartment of Women's and Children's Health Uppsala University and Uppsala University Children's Hospital Uppsala SwedenDepartment of Women's and Children's Health Uppsala University and Uppsala University Children's Hospital Uppsala SwedenAbstract Background Pilocytic astrocytoma is the most common brain tumour type in childhood located in the posterior fossa, and treated mainly with surgery. These tumours have low mortality, but knowledge concerning its long‐term outcome is sparse. Aims The aim was to investigate if patients treated for pilocytic astrocytoma in the posterior fossa had motor complications, including balance, motor and process skills. Methods and Results This descriptive single‐centre study includes eight children and 12 adults, treated for pilocytic astrocytoma as children. Motor performance was investigated with Bruininks–Oseretsky Test of Motor Proficiency, Second Edition, and dynamic balance with the mini‐balance evaluation systems test. Physiological cost index, six‐minute walk test, hand grip strength and assessment of motor and process skills were also evaluated. Ten patients reported motor difficulties, mainly from the upper limbs. The motor performance test showed results within normal limits except for manual dexterity, which was significantly below mean (p = .008). In the dynamic balance test patients had significantly lower results compared with controls (p = .036). Physiological cost index, six‐minute walk tests and hand grip strength showed results within normal limits. In the Assessment of Motor and Process Skills, patients over 16 years had significantly lower results compared with test norms for motor activities of daily living (ADL) and 30% of all patients scored below the cut‐off level for difficulties with motor skills. Conclusions Motor performance for patients treated for pilocytic astrocytoma in the posterior fossa in childhood is satisfactory but some patients display difficulties with balance, manual dexterity and ADL motor skills. Thus, it is important to identify those in need of motor follow‐up and training.https://doi.org/10.1002/cnr2.1548ADLbalancechildhoodmotor performancepilocytic astrocytomaposterior fossa |
| spellingShingle | Ingela Kristiansen Gunilla E. Frykberg Anette Höglund Annette Sondell Bo Strömberg Per Frisk Motor performance after treatment of pilocytic astrocytoma in the posterior fossa in childhood Cancer Reports ADL balance childhood motor performance pilocytic astrocytoma posterior fossa |
| title | Motor performance after treatment of pilocytic astrocytoma in the posterior fossa in childhood |
| title_full | Motor performance after treatment of pilocytic astrocytoma in the posterior fossa in childhood |
| title_fullStr | Motor performance after treatment of pilocytic astrocytoma in the posterior fossa in childhood |
| title_full_unstemmed | Motor performance after treatment of pilocytic astrocytoma in the posterior fossa in childhood |
| title_short | Motor performance after treatment of pilocytic astrocytoma in the posterior fossa in childhood |
| title_sort | motor performance after treatment of pilocytic astrocytoma in the posterior fossa in childhood |
| topic | ADL balance childhood motor performance pilocytic astrocytoma posterior fossa |
| url | https://doi.org/10.1002/cnr2.1548 |
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