SHMT2 regulates serine metabolism to promote the progression and immunosuppression of papillary renal cell carcinoma

SHMT2 regulates serine metabolism to promote the progression and immunosuppression of papillary renal cell carcinoma

Recent research has demonstrated the diverse relationship between tumour metabolism and the tumour microenvironment (TME), for example, abnormal serine metabolism. This study investigated the role of serine metabolism in papillary renal cell carcinoma (pRCC) focusing on the prognostic value and regu...

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Bibliographic Details
Main Authors: Weiyu Kong, Zhongyuan Wang, Nuoran Chen, Yiwen Mei, Yang Li, Yulin Yue
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
cancer metabolism
serine
tumour microenvironment
SHMT2
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.914332/full

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