The past and future of tuberculosis research.
Renewed efforts in tuberculosis (TB) research have led to important new insights into the biology and epidemiology of this devastating disease. Yet, in the face of the modern epidemics of HIV/AIDS, diabetes, and multidrug resistance--all of which contribute to susceptibility to TB--global control of...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-10-01
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| Series: | PLoS Pathogens |
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19855821/?tool=EBI |
| _version_ | 1818435596113149952 |
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| author | Iñaki Comas Sebastien Gagneux |
| author_facet | Iñaki Comas Sebastien Gagneux |
| author_sort | Iñaki Comas |
| collection | DOAJ |
| description | Renewed efforts in tuberculosis (TB) research have led to important new insights into the biology and epidemiology of this devastating disease. Yet, in the face of the modern epidemics of HIV/AIDS, diabetes, and multidrug resistance--all of which contribute to susceptibility to TB--global control of the disease will remain a formidable challenge for years to come. New high-throughput genomics technologies are already contributing to studies of TB's epidemiology, comparative genomics, evolution, and host-pathogen interaction. We argue here, however, that new multidisciplinary approaches--especially the integration of epidemiology with systems biology in what we call "systems epidemiology"--will be required to eliminate TB. |
| first_indexed | 2024-12-14T16:55:24Z |
| format | Article |
| id | doaj.art-173cb504a4ae4c15a6e319cffaf676fc |
| institution | Directory Open Access Journal |
| issn | 1553-7366 1553-7374 |
| language | English |
| last_indexed | 2024-12-14T16:55:24Z |
| publishDate | 2009-10-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS Pathogens |
| spelling | doaj.art-173cb504a4ae4c15a6e319cffaf676fc2022-12-21T22:53:58ZengPublic Library of Science (PLoS)PLoS Pathogens1553-73661553-73742009-10-01510e100060010.1371/journal.ppat.1000600The past and future of tuberculosis research.Iñaki ComasSebastien GagneuxRenewed efforts in tuberculosis (TB) research have led to important new insights into the biology and epidemiology of this devastating disease. Yet, in the face of the modern epidemics of HIV/AIDS, diabetes, and multidrug resistance--all of which contribute to susceptibility to TB--global control of the disease will remain a formidable challenge for years to come. New high-throughput genomics technologies are already contributing to studies of TB's epidemiology, comparative genomics, evolution, and host-pathogen interaction. We argue here, however, that new multidisciplinary approaches--especially the integration of epidemiology with systems biology in what we call "systems epidemiology"--will be required to eliminate TB.https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19855821/?tool=EBI |
| spellingShingle | Iñaki Comas Sebastien Gagneux The past and future of tuberculosis research. PLoS Pathogens |
| title | The past and future of tuberculosis research. |
| title_full | The past and future of tuberculosis research. |
| title_fullStr | The past and future of tuberculosis research. |
| title_full_unstemmed | The past and future of tuberculosis research. |
| title_short | The past and future of tuberculosis research. |
| title_sort | past and future of tuberculosis research |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19855821/?tool=EBI |
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