Plasma metabolome predicts trained immunity responses after antituberculosis BCG vaccination.

Plasma metabolome predicts trained immunity responses after antituberculosis BCG vaccination.

The antituberculosis vaccine Bacillus Calmette-Guérin (BCG) induces nonspecific protection against heterologous infections, at least partly through induction of innate immune memory (trained immunity). The amplitude of the response to BCG is variable, but the factors that influence this response are...

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Bibliographic Details
Main Authors: Valerie A C M Koeken, Cancan Qi, Vera P Mourits, L Charlotte J de Bree, Simone J C F M Moorlag, Vidhisha Sonawane, Heidi Lemmers, Helga Dijkstra, Leo A B Joosten, Arjan van Laarhoven, Cheng-Jian Xu, Reinout van Crevel, Mihai G Netea, Yang Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-09-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001765

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https://doi.org/10.1371/journal.pbio.3001765

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