NECAPs are negative regulators of the AP2 clathrin adaptor complex

NECAPs are negative regulators of the AP2 clathrin adaptor complex

Eukaryotic cells internalize transmembrane receptors via clathrin-mediated endocytosis, but it remains unclear how the machinery underpinning this process is regulated. We recently discovered that membrane-associated muniscin proteins such as FCHo and SGIP initiate endocytosis by converting the AP2...

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Bibliographic Details
Main Authors: Gwendolyn M Beacham, Edward A Partlow, Jeffrey J Lange, Gunther Hollopeter
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-01-01
Series:eLife
Subjects:
AP2
cell biology
clathrin adaptor complex
FCHo
endocytosis
NECAP
Online Access:https://elifesciences.org/articles/32242

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