Prospects of up-to-date antioxidants in the treatment of chronic eye diseases

According to the World Health Organization (WHO), about 285 million people are visually impaired, and, of those, around 39 million are blind and 246 million have low vision. About 90% of the world's visually impaired people live in low-income settings while 82% of people living with blindness a...

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Main Authors: O.P. Vitovska, L.D. Pichkur
Format: Article
Language:English
Published: Ukrainian Society of Ophthalmologists 2020-06-01
Series:Journal of Ophthalmology
Subjects:
Online Access:https://www.ozhurnal.com/en/archive/2020/3/8-fulltext
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author O.P. Vitovska
L.D. Pichkur
author_facet O.P. Vitovska
L.D. Pichkur
author_sort O.P. Vitovska
collection DOAJ
description According to the World Health Organization (WHO), about 285 million people are visually impaired, and, of those, around 39 million are blind and 246 million have low vision. About 90% of the world's visually impaired people live in low-income settings while 82% of people living with blindness are aged 50 and above; this age group represents 20% of the world's population. Age-related macular degeneration (AMD), glaucoma, cataract and diabetic retinopathy are the most common causes of legal blindness and visual impairment in Ukraine, and, today, the role of free radicals in the development of these disorders is indisputable. Astaxanthin is a powerful antioxidant, more effective than lutein or zeaxanthin. Since astaxanthin has a beneficial molecular structure and multifaceted mechanism of action, is highly bioavailable and capable of crossing the blood brain barrier, it might be promising in the treatment of chronic incapacitating disorders such as glaucoma, diabetic retinopathy and AMD.
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spelling doaj.art-17409765f56948dca07354e8042b36782023-12-18T15:40:24ZengUkrainian Society of OphthalmologistsJournal of Ophthalmology2412-87402020-06-013424610.31288/oftalmolzh202034246Prospects of up-to-date antioxidants in the treatment of chronic eye diseasesO.P. Vitovska0L.D. Pichkur1Bogomolets National Medical UniversityRomodanov Neurosurgery Institute, NAMS of UkraineAccording to the World Health Organization (WHO), about 285 million people are visually impaired, and, of those, around 39 million are blind and 246 million have low vision. About 90% of the world's visually impaired people live in low-income settings while 82% of people living with blindness are aged 50 and above; this age group represents 20% of the world's population. Age-related macular degeneration (AMD), glaucoma, cataract and diabetic retinopathy are the most common causes of legal blindness and visual impairment in Ukraine, and, today, the role of free radicals in the development of these disorders is indisputable. Astaxanthin is a powerful antioxidant, more effective than lutein or zeaxanthin. Since astaxanthin has a beneficial molecular structure and multifaceted mechanism of action, is highly bioavailable and capable of crossing the blood brain barrier, it might be promising in the treatment of chronic incapacitating disorders such as glaucoma, diabetic retinopathy and AMD.https://www.ozhurnal.com/en/archive/2020/3/8-fulltextoxidative stressamdglaucomadiabetic retinopathyantioxidantsastaxanthin
spellingShingle O.P. Vitovska
L.D. Pichkur
Prospects of up-to-date antioxidants in the treatment of chronic eye diseases
Journal of Ophthalmology
oxidative stress
amd
glaucoma
diabetic retinopathy
antioxidants
astaxanthin
title Prospects of up-to-date antioxidants in the treatment of chronic eye diseases
title_full Prospects of up-to-date antioxidants in the treatment of chronic eye diseases
title_fullStr Prospects of up-to-date antioxidants in the treatment of chronic eye diseases
title_full_unstemmed Prospects of up-to-date antioxidants in the treatment of chronic eye diseases
title_short Prospects of up-to-date antioxidants in the treatment of chronic eye diseases
title_sort prospects of up to date antioxidants in the treatment of chronic eye diseases
topic oxidative stress
amd
glaucoma
diabetic retinopathy
antioxidants
astaxanthin
url https://www.ozhurnal.com/en/archive/2020/3/8-fulltext
work_keys_str_mv AT opvitovska prospectsofuptodateantioxidantsinthetreatmentofchroniceyediseases
AT ldpichkur prospectsofuptodateantioxidantsinthetreatmentofchroniceyediseases