Synthesis of 2,4-disubstituted quinazolines promoted by deep eutectic solvent
An efficient deep eutectic solvent (DES) promoted reaction of 2-amino-5-chlorobenzophenone, aromatic aldehydes (benzoyl alcohols) and ammonium acetate leading to the formation of quinazolines with excellent yields is described. The use of expensive catalysts and organic solvents are avoided in this...
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| Format: | Article |
| Language: | English |
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Elsevier
2021-01-01
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| Series: | Current Research in Green and Sustainable Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666086521000771 |
| _version_ | 1819102298819788800 |
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| author | Rajkumar Romeshkumar Singh Thokchom Prasanta Singh Thangjam Linda Devi Thokchom Jeeta Devi Okram Mukherjee Singh |
| author_facet | Rajkumar Romeshkumar Singh Thokchom Prasanta Singh Thangjam Linda Devi Thokchom Jeeta Devi Okram Mukherjee Singh |
| author_sort | Rajkumar Romeshkumar Singh |
| collection | DOAJ |
| description | An efficient deep eutectic solvent (DES) promoted reaction of 2-amino-5-chlorobenzophenone, aromatic aldehydes (benzoyl alcohols) and ammonium acetate leading to the formation of quinazolines with excellent yields is described. The use of expensive catalysts and organic solvents are avoided in this protocol with the use of DES, which is biodegradable and renewable. |
| first_indexed | 2024-12-22T01:32:21Z |
| format | Article |
| id | doaj.art-1741b58cb0a448e1b43a7f3057174776 |
| institution | Directory Open Access Journal |
| issn | 2666-0865 |
| language | English |
| last_indexed | 2024-12-22T01:32:21Z |
| publishDate | 2021-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Current Research in Green and Sustainable Chemistry |
| spelling | doaj.art-1741b58cb0a448e1b43a7f30571747762022-12-21T18:43:28ZengElsevierCurrent Research in Green and Sustainable Chemistry2666-08652021-01-014100130Synthesis of 2,4-disubstituted quinazolines promoted by deep eutectic solventRajkumar Romeshkumar Singh0Thokchom Prasanta Singh1Thangjam Linda Devi2Thokchom Jeeta Devi3Okram Mukherjee Singh4Chemistry Department, Manipur University, Canchipur, 795003, Manipur, IndiaCorresponding author.; Chemistry Department, Manipur University, Canchipur, 795003, Manipur, IndiaChemistry Department, Manipur University, Canchipur, 795003, Manipur, IndiaChemistry Department, Manipur University, Canchipur, 795003, Manipur, IndiaCorresponding author.; Chemistry Department, Manipur University, Canchipur, 795003, Manipur, IndiaAn efficient deep eutectic solvent (DES) promoted reaction of 2-amino-5-chlorobenzophenone, aromatic aldehydes (benzoyl alcohols) and ammonium acetate leading to the formation of quinazolines with excellent yields is described. The use of expensive catalysts and organic solvents are avoided in this protocol with the use of DES, which is biodegradable and renewable.http://www.sciencedirect.com/science/article/pii/S2666086521000771Deep eutectic solventQuinazolineBenzyl alcoholBiodegradable |
| spellingShingle | Rajkumar Romeshkumar Singh Thokchom Prasanta Singh Thangjam Linda Devi Thokchom Jeeta Devi Okram Mukherjee Singh Synthesis of 2,4-disubstituted quinazolines promoted by deep eutectic solvent Current Research in Green and Sustainable Chemistry Deep eutectic solvent Quinazoline Benzyl alcohol Biodegradable |
| title | Synthesis of 2,4-disubstituted quinazolines promoted by deep eutectic solvent |
| title_full | Synthesis of 2,4-disubstituted quinazolines promoted by deep eutectic solvent |
| title_fullStr | Synthesis of 2,4-disubstituted quinazolines promoted by deep eutectic solvent |
| title_full_unstemmed | Synthesis of 2,4-disubstituted quinazolines promoted by deep eutectic solvent |
| title_short | Synthesis of 2,4-disubstituted quinazolines promoted by deep eutectic solvent |
| title_sort | synthesis of 2 4 disubstituted quinazolines promoted by deep eutectic solvent |
| topic | Deep eutectic solvent Quinazoline Benzyl alcohol Biodegradable |
| url | http://www.sciencedirect.com/science/article/pii/S2666086521000771 |
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