Synthesis of 2,4-disubstituted quinazolines promoted by deep eutectic solvent

Synthesis of 2,4-disubstituted quinazolines promoted by deep eutectic solvent

An efficient deep eutectic solvent (DES) promoted reaction of 2-amino-5-chlorobenzophenone, aromatic aldehydes (benzoyl alcohols) and ammonium acetate leading to the formation of quinazolines with excellent yields is described. The use of expensive catalysts and organic solvents are avoided in this...

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Bibliographic Details
Main Authors: Rajkumar Romeshkumar Singh, Thokchom Prasanta Singh, Thangjam Linda Devi, Thokchom Jeeta Devi, Okram Mukherjee Singh
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Current Research in Green and Sustainable Chemistry
Subjects:
Deep eutectic solvent
Quinazoline
Benzyl alcohol
Biodegradable
Online Access:http://www.sciencedirect.com/science/article/pii/S2666086521000771

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