Functionalized iron oxide nanoparticles: synthesis through ultrasonic-assisted co-precipitation and performance as hyperthermic agents for biomedical applications
Dual-functional iron oxide nanoparticles (IONPs), displaying self-heating and antibacterial effects are highly desired for biomedical application. This study involved the synthesis of functionalized IONPs coated with 3-aminopropyltriethoxysilane and polyethylene glycol via ultrasonic-assisted co-pre...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-06-01
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| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844022009422 |
| _version_ | 1818549112563302400 |
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| author | L.M. AL-Harbi Mohamed S.A. Darwish |
| author_facet | L.M. AL-Harbi Mohamed S.A. Darwish |
| author_sort | L.M. AL-Harbi |
| collection | DOAJ |
| description | Dual-functional iron oxide nanoparticles (IONPs), displaying self-heating and antibacterial effects are highly desired for biomedical application. This study involved the synthesis of functionalized IONPs coated with 3-aminopropyltriethoxysilane and polyethylene glycol via ultrasonic-assisted co-precipitation technique. The synthesized IONPs were then characterized by using Fourier-transform infrared spectroscopy, X-ray diffraction, dynamic light scattering, scanning electron microscopy, zeta potential, vibrating sample magnetometer and thermogravimetric analysis techniques. In addition, the effect of the synthesized IONPs on bacterial growth (S. aureus and E. coli) was studied. The influence of magnetic field power, as well as the viscous carriers on the heating efficiency of the synthesized IONPs was investigated. The specific absorption rate values increased as the power increased and decreased with the increase in the carrier viscosity. These characteristics render the synthesized iron oxide nanoparticles synthesized in the present study suitable for biomedical application as hyperthermic agents. |
| first_indexed | 2024-12-12T08:29:11Z |
| format | Article |
| id | doaj.art-1744e03ddb74459493354169bc4f6e22 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-12-12T08:29:11Z |
| publishDate | 2022-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-1744e03ddb74459493354169bc4f6e222022-12-22T00:31:09ZengElsevierHeliyon2405-84402022-06-0186e09654Functionalized iron oxide nanoparticles: synthesis through ultrasonic-assisted co-precipitation and performance as hyperthermic agents for biomedical applicationsL.M. AL-Harbi0Mohamed S.A. Darwish1Chemistry Department, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah, 21589, Saudi ArabiaEgyptian Petroleum Research Institute, 1 Ahmed El-Zomor Street, El Zohour Region, Nasr City, Cairo, 11727, Egypt; Corresponding author.Dual-functional iron oxide nanoparticles (IONPs), displaying self-heating and antibacterial effects are highly desired for biomedical application. This study involved the synthesis of functionalized IONPs coated with 3-aminopropyltriethoxysilane and polyethylene glycol via ultrasonic-assisted co-precipitation technique. The synthesized IONPs were then characterized by using Fourier-transform infrared spectroscopy, X-ray diffraction, dynamic light scattering, scanning electron microscopy, zeta potential, vibrating sample magnetometer and thermogravimetric analysis techniques. In addition, the effect of the synthesized IONPs on bacterial growth (S. aureus and E. coli) was studied. The influence of magnetic field power, as well as the viscous carriers on the heating efficiency of the synthesized IONPs was investigated. The specific absorption rate values increased as the power increased and decreased with the increase in the carrier viscosity. These characteristics render the synthesized iron oxide nanoparticles synthesized in the present study suitable for biomedical application as hyperthermic agents.http://www.sciencedirect.com/science/article/pii/S2405844022009422Functionalized iron oxide nanoparticlesSpecific absorption rateHyperthermiaBiomedical applications |
| spellingShingle | L.M. AL-Harbi Mohamed S.A. Darwish Functionalized iron oxide nanoparticles: synthesis through ultrasonic-assisted co-precipitation and performance as hyperthermic agents for biomedical applications Heliyon Functionalized iron oxide nanoparticles Specific absorption rate Hyperthermia Biomedical applications |
| title | Functionalized iron oxide nanoparticles: synthesis through ultrasonic-assisted co-precipitation and performance as hyperthermic agents for biomedical applications |
| title_full | Functionalized iron oxide nanoparticles: synthesis through ultrasonic-assisted co-precipitation and performance as hyperthermic agents for biomedical applications |
| title_fullStr | Functionalized iron oxide nanoparticles: synthesis through ultrasonic-assisted co-precipitation and performance as hyperthermic agents for biomedical applications |
| title_full_unstemmed | Functionalized iron oxide nanoparticles: synthesis through ultrasonic-assisted co-precipitation and performance as hyperthermic agents for biomedical applications |
| title_short | Functionalized iron oxide nanoparticles: synthesis through ultrasonic-assisted co-precipitation and performance as hyperthermic agents for biomedical applications |
| title_sort | functionalized iron oxide nanoparticles synthesis through ultrasonic assisted co precipitation and performance as hyperthermic agents for biomedical applications |
| topic | Functionalized iron oxide nanoparticles Specific absorption rate Hyperthermia Biomedical applications |
| url | http://www.sciencedirect.com/science/article/pii/S2405844022009422 |
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