High fat diets induce early changes in gut microbiota that may serve as markers of ulterior altered physiological and biochemical parameters related to metabolic syndrome. Effect of virgin olive oil in comparison to butter
Butter and virgin olive oil (EVOO) are two fats differing in their degree of saturation and insaponifiable fraction. EVOO, enriched in polyphenols and other minority components, exerts a distinct effect on health. Using next generation sequencing, we have studied early and long-term effects of both...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2022-01-01
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| Series: | PLoS ONE |
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380944/?tool=EBI |
| _version_ | 1811340775635550208 |
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| author | Natalia Andújar-Tenorio Isabel Prieto Antonio Cobo Ana M. Martínez-Rodríguez Marina Hidalgo Ana Belén Segarra Manuel Ramírez Antonio Gálvez Magdalena Martínez-Cañamero |
| author_facet | Natalia Andújar-Tenorio Isabel Prieto Antonio Cobo Ana M. Martínez-Rodríguez Marina Hidalgo Ana Belén Segarra Manuel Ramírez Antonio Gálvez Magdalena Martínez-Cañamero |
| author_sort | Natalia Andújar-Tenorio |
| collection | DOAJ |
| description | Butter and virgin olive oil (EVOO) are two fats differing in their degree of saturation and insaponifiable fraction. EVOO, enriched in polyphenols and other minority components, exerts a distinct effect on health. Using next generation sequencing, we have studied early and long-term effects of both types of fats on the intestinal microbiota of mice, finding significant differences between the two diets in the percentage of certain bacterial taxa, correlating with hormonal, physiological and metabolic parameters in the host. These correlations are not only concomitant, but most noticeably some of the changes detected in the microbial percentages at six weeks are correlating with changes in physiological values detected later, at twelve weeks. Desulfovibrionaceae/Desulfovibrio/D. sulfuricans stand out by presenting at six weeks a statistically significant higher percentage in the butter-fed mice with respect to the EVOO group, correlating with systolic blood pressure, food intake, water intake and insulin at twelve weeks. This not only suggests an early implication in the probability of developing altered physiological and biochemical responses later on in the host lifespan, but also opens the possibility of using this genus as a marker in the risk of suffering different pathologies in the future. |
| first_indexed | 2024-04-13T18:46:54Z |
| format | Article |
| id | doaj.art-17471a76311f49e184c6c0c46b612721 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-13T18:46:54Z |
| publishDate | 2022-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-17471a76311f49e184c6c0c46b6127212022-12-22T02:34:33ZengPublic Library of Science (PLoS)PLoS ONE1932-62032022-01-01178High fat diets induce early changes in gut microbiota that may serve as markers of ulterior altered physiological and biochemical parameters related to metabolic syndrome. Effect of virgin olive oil in comparison to butterNatalia Andújar-TenorioIsabel PrietoAntonio CoboAna M. Martínez-RodríguezMarina HidalgoAna Belén SegarraManuel RamírezAntonio GálvezMagdalena Martínez-CañameroButter and virgin olive oil (EVOO) are two fats differing in their degree of saturation and insaponifiable fraction. EVOO, enriched in polyphenols and other minority components, exerts a distinct effect on health. Using next generation sequencing, we have studied early and long-term effects of both types of fats on the intestinal microbiota of mice, finding significant differences between the two diets in the percentage of certain bacterial taxa, correlating with hormonal, physiological and metabolic parameters in the host. These correlations are not only concomitant, but most noticeably some of the changes detected in the microbial percentages at six weeks are correlating with changes in physiological values detected later, at twelve weeks. Desulfovibrionaceae/Desulfovibrio/D. sulfuricans stand out by presenting at six weeks a statistically significant higher percentage in the butter-fed mice with respect to the EVOO group, correlating with systolic blood pressure, food intake, water intake and insulin at twelve weeks. This not only suggests an early implication in the probability of developing altered physiological and biochemical responses later on in the host lifespan, but also opens the possibility of using this genus as a marker in the risk of suffering different pathologies in the future.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380944/?tool=EBI |
| spellingShingle | Natalia Andújar-Tenorio Isabel Prieto Antonio Cobo Ana M. Martínez-Rodríguez Marina Hidalgo Ana Belén Segarra Manuel Ramírez Antonio Gálvez Magdalena Martínez-Cañamero High fat diets induce early changes in gut microbiota that may serve as markers of ulterior altered physiological and biochemical parameters related to metabolic syndrome. Effect of virgin olive oil in comparison to butter PLoS ONE |
| title | High fat diets induce early changes in gut microbiota that may serve as markers of ulterior altered physiological and biochemical parameters related to metabolic syndrome. Effect of virgin olive oil in comparison to butter |
| title_full | High fat diets induce early changes in gut microbiota that may serve as markers of ulterior altered physiological and biochemical parameters related to metabolic syndrome. Effect of virgin olive oil in comparison to butter |
| title_fullStr | High fat diets induce early changes in gut microbiota that may serve as markers of ulterior altered physiological and biochemical parameters related to metabolic syndrome. Effect of virgin olive oil in comparison to butter |
| title_full_unstemmed | High fat diets induce early changes in gut microbiota that may serve as markers of ulterior altered physiological and biochemical parameters related to metabolic syndrome. Effect of virgin olive oil in comparison to butter |
| title_short | High fat diets induce early changes in gut microbiota that may serve as markers of ulterior altered physiological and biochemical parameters related to metabolic syndrome. Effect of virgin olive oil in comparison to butter |
| title_sort | high fat diets induce early changes in gut microbiota that may serve as markers of ulterior altered physiological and biochemical parameters related to metabolic syndrome effect of virgin olive oil in comparison to butter |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380944/?tool=EBI |
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