Immunohistochemical detection of MUC5AC and MUC5B mucins in ferrets

Immunohistochemical detection of MUC5AC and MUC5B mucins in ferrets

Abstract Objective Cystic fibrosis (CF) is a genetic condition that causes abnormal mucus secretions in affected organs. MUC5AC and MUC5B are gel-forming mucins and frequent targets for investigations in CF tissues. Our objective was to qualify MUC5AC and MUC5B immunohistochemical techniques to prov...

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Bibliographic Details
Main Authors: David K. Meyerholz, Mariah R. Leidinger, J. Adam Goeken, Thomas R. Businga, Sebastian Vizuett, Allison Akers, Idil Evans, Yan Zhang, John F. Engelhardt
Format: Article
Language:English
Published: BMC 2023-06-01
Series:BMC Research Notes
Subjects:
Cystic fibrosis
Ferret
Immunohistochemistry
Lung
Mucin
Mucus
Online Access:https://doi.org/10.1186/s13104-023-06388-x

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