<b>Effect of binders on 500mg metformin hydrochloride tablets produced by wet granulation</b>

<b>Effect of binders on 500mg metformin hydrochloride tablets produced by wet granulation</b>

Metformin hydrochloride (MH) is an oral hypoglycemic agent and a high-dose drug that has poor flow and compression properties. In this study, the feasibility of developing adequate, low cost 500mg tablets of metformin hydrochloride by wet granulation was tested with several binders (Starch / PVP K30...

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Bibliographic Details
Main Authors: LUCIANA CATIA BLOCK, LEONARDO OLIVEIRA SCHMELING, ANGELICA GARCIA COUTO, MARCOS ANTONIO SEGATTO, MONIKA P TAGLIARI, TANIA MARI BELLE BRESOLIN, SAMANTA CARDOZO MOURãO
Format: Article
Language:English
Published: São Paulo State University (UNESP) 2009-12-01
Series:Revista de Ciências Farmacêuticas Básica e Aplicada
Subjects:
metformin hydrochloride
tablets
wet granulation
binders
Online Access:http://serv-bib.fcfar.unesp.br/seer/index.php/Cien_Farm/article/view/614

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