Effects of different doses of methylprednisolone therapy on acute respiratory distress syndrome: results from animal and clinical studies

Effects of different doses of methylprednisolone therapy on acute respiratory distress syndrome: results from animal and clinical studies

Abstract Background The optimal dose of glucocorticoids for acute respiratory distress syndrome (ARDS) is uncertain. This study aimed to evaluate the effects of different doses of methylprednisolone on sepsis-induced acute lung injury (ALI) rats and a cohort of moderate and severe ARDS patients. Met...

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Bibliographic Details
Main Authors: Shukun Hong, Chao Jian, Hongye Wang, Xincheng Wang, Luchuan Xing, Lujun Qiao
Format: Article
Language:English
Published: BMC 2022-09-01
Series:BMC Pulmonary Medicine
Subjects:
Glucocorticoids
Methylprednisolone
Acute lung injury
Acute respiratory distress syndrome
Dose
Animal model
Online Access:https://doi.org/10.1186/s12890-022-02148-y

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