The mechanism of Annexin A1 to modulate TRPV1 and nociception in dorsal root ganglion neurons

The mechanism of Annexin A1 to modulate TRPV1 and nociception in dorsal root ganglion neurons

Abstract Background Annexin A1 (ANXA1) exerts anti-nociceptive effect through ANXA1 receptor formyl peptide receptor 2 (FPR2/ALX (receptor for lipoxin A4), FPR2) at the dorsal root ganglia (DRG) level. However, the mechanisms remain elucidated. By using radiant heat, hot/cold plate, tail flick, von...

Full description

Bibliographic Details
Main Authors:	Yufen Zhang, Sehui Ma, Xiao Ke, Yao Yi, Hongyan Yu, Dian Yu, Qiang Li, You Shang, Youming Lu, Lei Pei
Format:	Article
Language:	English
Published:	BMC 2021-08-01
Series:	Cell & Bioscience
Subjects:	Annexin A1 Formyl peptide receptor Neuronal sensitivity Nociceptive sensation Transient receptor potential vanilloid 1
Online Access:	https://doi.org/10.1186/s13578-021-00679-1

Similar Items

New Insights on Formyl Peptide Receptor Type 2 Involvement in Nociceptive Processes in the Spinal Cord
by: Mariantonella Colucci, et al.
Published: (2022-03-01)

Therapeutic Potential of Annexin A1 in Ischemia Reperfusion Injury
by: Junaid Ansari, et al.
Published: (2018-04-01)

Anatomical Analysis of Transient Potential Vanilloid Receptor 1 (Trpv1+) and Mu-Opioid Receptor (Oprm1+) Co-expression in Rat Dorsal Root Ganglion Neurons
by: Wenting Ma, et al.
Published: (2022-07-01)

TRPV1: A Target for Rational Drug Design
by: Vincenzo Carnevale, et al.
Published: (2016-08-01)

Cardioprotective Actions of the Annexin-A1 N-Terminal Peptide, Ac2-26, Against Myocardial Infarction
by: Cheng Xue Qin, et al.
Published: (2019-04-01)

Real-Time Translocation and Function of PKCβII Isoform in Response to Nociceptive Signaling via the TRPV1 Pain Receptor
by: Basil D. Roufogalis, et al.
Published: (2011-11-01)

Interleukin-6 Signaling in Triple Negative Breast Cancer Cells Elicits the Annexin A1/Formyl Peptide Receptor 1 Axis and Affects the Tumor Microenvironment
by: Lara Vecchi, et al.
Published: (2022-05-01)

Exploring the antinociceptive potential of homoeriodictyol in nociception models
by: Manal H. Al-Bzour, et al.
Published: (2024-07-01)

Lysionotin exerts antinociceptive effects in various models of nociception induction
by: Abdelrahim Alqudah, et al.
Published: (2023-04-01)

Morphine Reduces Expression of TRPV1 Receptors in the Amygdala but not in the Hippocampus of Male Rats
by: Elham Hakimizadeh, et al.
Published: (2014-05-01)

Emerging Families of Ion Channels Involved in Urinary Bladder Nociception
by: Yusaku Okada, et al.
Published: (2010-07-01)

Targeting AnxA1/Formyl Peptide Receptor 2 Pathway Affords Protection against Pathological Thrombo-Inflammation
by: Shantel A. Vital, et al.
Published: (2020-11-01)

Defective formyl peptide receptor 2/3 and annexin A1 expressions associated with M2a polarization of blood immune cells in patients with chronic obstructive pulmonary disease
by: Yung-Che Chen, et al.
Published: (2018-03-01)

Annexin A1 protects against cerebral ischemia–reperfusion injury by modulating microglia/macrophage polarization via FPR2/ALX-dependent AMPK-mTOR pathway
by: Xin Xu, et al.
Published: (2021-05-01)

The Vanilloid (Capsaicin) Receptor TRPV1 in Blood Pressure Regulation: A Novel Therapeutic Target in Hypertension?
by: Arpad Szallasi
Published: (2023-05-01)

Modulation of TRPV1 on Odontoblast-like Cells Using Capsazepine-Loaded Nanogels
by: Lilia Jadith Bernal-Cepeda, et al.
Published: (2024-03-01)

CC chemokine ligand 2 upregulates the current density and expression of TRPV1 channels and Na<sub>v</sub>1.8 sodium channels in dorsal root ganglion neurons
by: Kao Der-Jang, et al.
Published: (2012-08-01)

Mitocryptide-2: Identification of Its Minimum Structure for Specific Activation of FPR2–Possible Receptor Switching from FPR2 to FPR1 by Its Physiological C-terminal Cleavages
by: Takayuki Marutani, et al.
Published: (2021-04-01)

Intracellular aggregated TRPV1 is associated with lower survival in breast cancer patients
by: Lozano C, et al.
Published: (2018-10-01)

Inhibition of Spinal TRPV1 Reduces NMDA Receptor 2B Phosphorylation and Produces Anti-Nociceptive Effects in Mice with Inflammatory Pain
by: Suk-Yun Kang, et al.
Published: (2021-10-01)

Transient receptor potential vanilloid-1 (TRPV1) channels act as suppressors of the growth of glioma
by: Jingjing Cheng, et al.
Published: (2024-06-01)

Novel TRPV1 Channel Agonists With Faster and More Potent Analgesic Properties Than Capsaicin
by: Yorley Duarte, et al.
Published: (2020-07-01)

TRPV1 Antagonists and Chronic Pain: Beyond Thermal Perception
by: Michael R. Brandt, et al.
Published: (2012-02-01)

Effects of Intrathecal administration of capsaicin and intraperitoneal administration of naloxone on anti-nociceptive function of heated Cannabis sativa female flowers hydroalcoholic extract
by: Bahram Farhadi Moghadam, et al.
Published: (2020-11-01)

Positive allosteric modulation of TRPV1 as a novel analgesic mechanism
by: Lebovitz Evan E, et al.
Published: (2012-09-01)

TRPV1 Receptor Identification in Bovine and Canine Mitral Valvular Interstitial Cells
by: Cristina Vercelli, et al.
Published: (2021-09-01)

Molecular Mechanisms of Dicentra Formosa’s Analgesic Effect
by: Royale Gray-Lee, et al.
Published: (2020-12-01)

The formyl peptide receptor agonist Ac2-26 alleviates neuroinflammation in a mouse model of pneumococcal meningitis
by: Marvin Rüger, et al.
Published: (2020-10-01)

Insulin Confers Differing Effects on Neurite Outgrowth in Separate Populations of Cultured Dorsal Root Ganglion Neurons: The Role of the Insulin Receptor
by: Bence András Lázár, et al.
Published: (2018-10-01)

Antidiabetic Effect of Rehmanniae Radix Based on Regulation of TRPV1 and SCD1
by: Ye Liu, et al.
Published: (2022-05-01)

Capsaicin alleviates the intestinal oxidative stress via activation of TRPV1/PKA/UCP2 and Keap1/Nrf2 pathways in heat-stressed mice
by: Zhihua Li, et al.
Published: (2023-09-01)

Nociceptive Pathway in the Cockroach Periplaneta americana
by: Stav Emanuel, et al.
Published: (2019-08-01)

Role of TRPV1 in High Temperature-Induced Mitochondrial Biogenesis in Skeletal Muscle: A Mini Review
by: Yixiao Xu, et al.
Published: (2022-04-01)

Generation of a CRF1-Cre transgenic rat and the role of central amygdala CRF1 cells in nociception and anxiety-like behavior
by: Marcus M Weera, et al.
Published: (2022-04-01)

Somatotopic localization of c-Fos expression in the spinal cord in response to noxious heat sensation
by: Safa Shehab, et al.
Published: (2022-09-01)

TRPV1 Tunes Optic Nerve Axon Excitability in Glaucoma
by: Nolan R. McGrady, et al.
Published: (2020-03-01)

Sensitization and translocation of TRPV1 by insulin and IGF-I
by: Pauza Mary E, et al.
Published: (2005-04-01)

The Role of Nociceptive Neurons in the Pathogenesis of Psoriasis
by: Xuan Zhang, et al.
Published: (2020-09-01)

TRPV1 Gates Tissue Access and Sustains Pathogenicity in Autoimmune Encephalitis
by: Geoffrey Paltser, et al.
Published: (2013-05-01)

Midbrain Dopamine Neurons Defined by TrpV1 Modulate Psychomotor Behavior
by: Gian Pietro Serra, et al.
Published: (2021-11-01)