Manifestations of tuberculous infection in children with a positive result of the test with tuberculosis recombinant allergen
The objective: to study manifestations of tuberculous infection in children with a positive result of the test with TRA and determine the tactics for their follow-up.Subjects and methods. In 217 children with a positive result of the test with tuberculosis recombinant allergen (TRA) followed up in a...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2019-09-01
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| Series: | Туберкулез и болезни лёгких |
| Subjects: | |
| Online Access: | https://www.tibl-journal.com/jour/article/view/1323 |
| _version_ | 1826563031003299840 |
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| author | E. P. Shilova L. V. Poddubnaya I. M. Stepchenko |
| author_facet | E. P. Shilova L. V. Poddubnaya I. M. Stepchenko |
| author_sort | E. P. Shilova |
| collection | DOAJ |
| description | The objective: to study manifestations of tuberculous infection in children with a positive result of the test with TRA and determine the tactics for their follow-up.Subjects and methods. In 217 children with a positive result of the test with tuberculosis recombinant allergen (TRA) followed up in a TB dispensary, the results of clinical and radiological (multispiral computed tomography MSCT) examinations were studied and the response to the test with TRA during monitoring (within 3 years) was evaluated to justify terms of dispensary follow-up.Results. It was found that the test with TRA and MSCT allows diagnosing both latent tuberculous infection and detecting minimal post-tuberculous changes (calcifications). Monitoring was performed in 2 groups: Group 1 (n = 112) included patients with newly detected calcifications in the lungs and chest lymph nodes, Group 2 (n = 105) consisted of patients without detected changes in the lungs and chest lymph nodes. The frequency of hyperergic reactions to the test with TRA recorded in patients of both groups was the same (46.7 ± 4.4 and 48.2 ± 4.7%). Results of the test with TRA in children without radiological changes stabilized two years, and in case of calcifications - in three years of follow-up, which allowed predicting the terms of follow-up for such children as belonging to tuberculosis risk group. |
| first_indexed | 2024-03-12T18:40:29Z |
| format | Article |
| id | doaj.art-174db5d7359f4ddc9adf1b15b3e5f8f4 |
| institution | Directory Open Access Journal |
| issn | 2075-1230 2542-1506 |
| language | Russian |
| last_indexed | 2025-03-14T09:57:29Z |
| publishDate | 2019-09-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Туберкулез и болезни лёгких |
| spelling | doaj.art-174db5d7359f4ddc9adf1b15b3e5f8f42025-03-02T11:22:31ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062019-09-01978323710.21292/2075-1230-2019-97-8-32-371323Manifestations of tuberculous infection in children with a positive result of the test with tuberculosis recombinant allergenE. P. Shilova0L. V. Poddubnaya1I. M. Stepchenko2Novosibirsk State Medical UniversityNovosibirsk State Medical UniversityOb Central City HospitalThe objective: to study manifestations of tuberculous infection in children with a positive result of the test with TRA and determine the tactics for their follow-up.Subjects and methods. In 217 children with a positive result of the test with tuberculosis recombinant allergen (TRA) followed up in a TB dispensary, the results of clinical and radiological (multispiral computed tomography MSCT) examinations were studied and the response to the test with TRA during monitoring (within 3 years) was evaluated to justify terms of dispensary follow-up.Results. It was found that the test with TRA and MSCT allows diagnosing both latent tuberculous infection and detecting minimal post-tuberculous changes (calcifications). Monitoring was performed in 2 groups: Group 1 (n = 112) included patients with newly detected calcifications in the lungs and chest lymph nodes, Group 2 (n = 105) consisted of patients without detected changes in the lungs and chest lymph nodes. The frequency of hyperergic reactions to the test with TRA recorded in patients of both groups was the same (46.7 ± 4.4 and 48.2 ± 4.7%). Results of the test with TRA in children without radiological changes stabilized two years, and in case of calcifications - in three years of follow-up, which allowed predicting the terms of follow-up for such children as belonging to tuberculosis risk group.https://www.tibl-journal.com/jour/article/view/1323latent tuberculosis infectiondormant tuberculosis infectiontest with tuberculous recombinant allergenmantoux test with 2 tu ppd-lchanges in the results of tests with tuberculous recombinant allergencalcification |
| spellingShingle | E. P. Shilova L. V. Poddubnaya I. M. Stepchenko Manifestations of tuberculous infection in children with a positive result of the test with tuberculosis recombinant allergen Туберкулез и болезни лёгких latent tuberculosis infection dormant tuberculosis infection test with tuberculous recombinant allergen mantoux test with 2 tu ppd-l changes in the results of tests with tuberculous recombinant allergen calcification |
| title | Manifestations of tuberculous infection in children with a positive result of the test with tuberculosis recombinant allergen |
| title_full | Manifestations of tuberculous infection in children with a positive result of the test with tuberculosis recombinant allergen |
| title_fullStr | Manifestations of tuberculous infection in children with a positive result of the test with tuberculosis recombinant allergen |
| title_full_unstemmed | Manifestations of tuberculous infection in children with a positive result of the test with tuberculosis recombinant allergen |
| title_short | Manifestations of tuberculous infection in children with a positive result of the test with tuberculosis recombinant allergen |
| title_sort | manifestations of tuberculous infection in children with a positive result of the test with tuberculosis recombinant allergen |
| topic | latent tuberculosis infection dormant tuberculosis infection test with tuberculous recombinant allergen mantoux test with 2 tu ppd-l changes in the results of tests with tuberculous recombinant allergen calcification |
| url | https://www.tibl-journal.com/jour/article/view/1323 |
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