Antiglycation potential of commercial available extracts of two Indian medicinal plants: Pterocarpus marsupium and Artocarpus lakoocha using advanced glycation end products (AGE) competitive fluorescence assay
Glycation is a non-enzymatic biochemical reaction between reducing sugars and amino acids, causing the crosslinking and rearrangement of glycated proteins, leading to irreversible formation of Advanced Glycation End products (AGEs). Glycation is an activity that occurred both endogenously in our bod...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2021-01-01
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| Series: | Cogent Food & Agriculture |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/23311932.2021.1914907 |
| _version_ | 1819283041963474944 |
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| author | Alpana Pande Lakshmi Mundkur Anurag Pande Sarang Bani Muhammed Majeed |
| author_facet | Alpana Pande Lakshmi Mundkur Anurag Pande Sarang Bani Muhammed Majeed |
| author_sort | Alpana Pande |
| collection | DOAJ |
| description | Glycation is a non-enzymatic biochemical reaction between reducing sugars and amino acids, causing the crosslinking and rearrangement of glycated proteins, leading to irreversible formation of Advanced Glycation End products (AGEs). Glycation is an activity that occurred both endogenously in our body and exposed to it through our diet as well, which contributed to the pool of AGEs and their pathology. AGEs played important role in various health conditions including and not limited to, hyperglycemia, inflammation, Alzheimer’s disease, cardiovascular health and, ageing itself. While the formation of AGEs is irreversible, its formation can be inhibited or slowed down by natural products, which have anti-glycation activity. In this study, we explored the antiglycation activity of commercial herbal extracts of Artocarpus lakoocha and Pterocarpus marsupium using a competitive fluorescence assay. Both Artocarpus lakoocha and Pterocarpus marsupium extracts show highest anti-glycation activity (84.6–100%) after background correction, in a range of 10 to 100 mg/ml. |
| first_indexed | 2024-12-24T01:25:11Z |
| format | Article |
| id | doaj.art-174dcc69f8444d0bb99fd02cb3ba0e59 |
| institution | Directory Open Access Journal |
| issn | 2331-1932 |
| language | English |
| last_indexed | 2024-12-24T01:25:11Z |
| publishDate | 2021-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Cogent Food & Agriculture |
| spelling | doaj.art-174dcc69f8444d0bb99fd02cb3ba0e592022-12-21T17:22:32ZengTaylor & Francis GroupCogent Food & Agriculture2331-19322021-01-017110.1080/23311932.2021.19149071914907Antiglycation potential of commercial available extracts of two Indian medicinal plants: Pterocarpus marsupium and Artocarpus lakoocha using advanced glycation end products (AGE) competitive fluorescence assayAlpana Pande0Lakshmi Mundkur1Anurag Pande2Sarang Bani3Muhammed Majeed4Sabinsa Corporation, East WindsorSami Labs LimitedSabinsa Corporation, East WindsorSami Labs LimitedSabinsa Corporation, East WindsorGlycation is a non-enzymatic biochemical reaction between reducing sugars and amino acids, causing the crosslinking and rearrangement of glycated proteins, leading to irreversible formation of Advanced Glycation End products (AGEs). Glycation is an activity that occurred both endogenously in our body and exposed to it through our diet as well, which contributed to the pool of AGEs and their pathology. AGEs played important role in various health conditions including and not limited to, hyperglycemia, inflammation, Alzheimer’s disease, cardiovascular health and, ageing itself. While the formation of AGEs is irreversible, its formation can be inhibited or slowed down by natural products, which have anti-glycation activity. In this study, we explored the antiglycation activity of commercial herbal extracts of Artocarpus lakoocha and Pterocarpus marsupium using a competitive fluorescence assay. Both Artocarpus lakoocha and Pterocarpus marsupium extracts show highest anti-glycation activity (84.6–100%) after background correction, in a range of 10 to 100 mg/ml.http://dx.doi.org/10.1080/23311932.2021.1914907glycationadvanced glycation end productsfluorescencepterostilbeneoxyresveratrol |
| spellingShingle | Alpana Pande Lakshmi Mundkur Anurag Pande Sarang Bani Muhammed Majeed Antiglycation potential of commercial available extracts of two Indian medicinal plants: Pterocarpus marsupium and Artocarpus lakoocha using advanced glycation end products (AGE) competitive fluorescence assay Cogent Food & Agriculture glycation advanced glycation end products fluorescence pterostilbene oxyresveratrol |
| title | Antiglycation potential of commercial available extracts of two Indian medicinal plants: Pterocarpus marsupium and Artocarpus lakoocha using advanced glycation end products (AGE) competitive fluorescence assay |
| title_full | Antiglycation potential of commercial available extracts of two Indian medicinal plants: Pterocarpus marsupium and Artocarpus lakoocha using advanced glycation end products (AGE) competitive fluorescence assay |
| title_fullStr | Antiglycation potential of commercial available extracts of two Indian medicinal plants: Pterocarpus marsupium and Artocarpus lakoocha using advanced glycation end products (AGE) competitive fluorescence assay |
| title_full_unstemmed | Antiglycation potential of commercial available extracts of two Indian medicinal plants: Pterocarpus marsupium and Artocarpus lakoocha using advanced glycation end products (AGE) competitive fluorescence assay |
| title_short | Antiglycation potential of commercial available extracts of two Indian medicinal plants: Pterocarpus marsupium and Artocarpus lakoocha using advanced glycation end products (AGE) competitive fluorescence assay |
| title_sort | antiglycation potential of commercial available extracts of two indian medicinal plants pterocarpus marsupium and artocarpus lakoocha using advanced glycation end products age competitive fluorescence assay |
| topic | glycation advanced glycation end products fluorescence pterostilbene oxyresveratrol |
| url | http://dx.doi.org/10.1080/23311932.2021.1914907 |
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