Characteristics of central compartment lymph node metastasis in patients with unilateral cN0 papillary thyroid carcinoma and prophylactic dissection
Objective To study the central compartment lymph node (CLN) metastasis in patients with unilateral pa-pillary thyroid carcinoma(PTC) diagnosed preoperatively and prophylactic dissection. Methods The data of 342 patients with unilateral PTC at cN0 stage who underwent unilateral thyroidectomy, isthmus...
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| Format: | Article |
| Language: | zho |
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Editorial Office of Journal of Surgery Concepts & Practice
2021-03-01
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| Series: | Waike lilun yu shijian |
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| Online Access: | https://www.qk.sjtu.edu.cn/jscp/fileup/1007-9610/PDF/1658864436469-2121370401.pdf |
| _version_ | 1797648484735647744 |
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| author | LIU Wei, WANG Cong, XUE Anwei, ZHAO Junjie, WANG Zhenglin |
| author_facet | LIU Wei, WANG Cong, XUE Anwei, ZHAO Junjie, WANG Zhenglin |
| author_sort | LIU Wei, WANG Cong, XUE Anwei, ZHAO Junjie, WANG Zhenglin |
| collection | DOAJ |
| description | Objective To study the central compartment lymph node (CLN) metastasis in patients with unilateral pa-pillary thyroid carcinoma(PTC) diagnosed preoperatively and prophylactic dissection. Methods The data of 342 patients with unilateral PTC at cN0 stage who underwent unilateral thyroidectomy, isthmusectomy and prophylactic CLN dissection were analyzed retrospectively in our department from January 2016 to December 2018. The characteristics of CLN metastasis were analyzed. Results Among 342 patients, 188(55.0%) patients had CLN metastasis. CLN metastasis was significantly related with age (P<0.001), sex (P<0.001), maximum diameter of tumor (P=0.001), capsular invasion (P=0.046), and more CLN (P<0.001). Metastatic CLN density is the metastatic CLN%, which was significantly related with sex (P=0.023) and capsular invasion (P=0.004). There was only one case with cervical hematoma and reoperation among all cases in this study. Two cases had temporary recurrent laryngeal nerve paralysis. Conclusions CLN metastasis in unilateral cN0 PTC patients was characterized with relation to sex, age, and lymph node density. Therefore prophylactic CLN dissection is necessary and safe for unilateral cN0 PTC patients. |
| first_indexed | 2024-03-11T15:32:47Z |
| format | Article |
| id | doaj.art-174e360c86a8430193426a7d8cc5aab2 |
| institution | Directory Open Access Journal |
| issn | 1007-9610 |
| language | zho |
| last_indexed | 2024-03-11T15:32:47Z |
| publishDate | 2021-03-01 |
| publisher | Editorial Office of Journal of Surgery Concepts & Practice |
| record_format | Article |
| series | Waike lilun yu shijian |
| spelling | doaj.art-174e360c86a8430193426a7d8cc5aab22023-10-27T02:12:49ZzhoEditorial Office of Journal of Surgery Concepts & PracticeWaike lilun yu shijian1007-96102021-03-01260215916210.16139/j.1007-9610.2021.02.013Characteristics of central compartment lymph node metastasis in patients with unilateral cN0 papillary thyroid carcinoma and prophylactic dissectionLIU Wei, WANG Cong, XUE Anwei, ZHAO Junjie, WANG Zhenglin0Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, ChinaObjective To study the central compartment lymph node (CLN) metastasis in patients with unilateral pa-pillary thyroid carcinoma(PTC) diagnosed preoperatively and prophylactic dissection. Methods The data of 342 patients with unilateral PTC at cN0 stage who underwent unilateral thyroidectomy, isthmusectomy and prophylactic CLN dissection were analyzed retrospectively in our department from January 2016 to December 2018. The characteristics of CLN metastasis were analyzed. Results Among 342 patients, 188(55.0%) patients had CLN metastasis. CLN metastasis was significantly related with age (P<0.001), sex (P<0.001), maximum diameter of tumor (P=0.001), capsular invasion (P=0.046), and more CLN (P<0.001). Metastatic CLN density is the metastatic CLN%, which was significantly related with sex (P=0.023) and capsular invasion (P=0.004). There was only one case with cervical hematoma and reoperation among all cases in this study. Two cases had temporary recurrent laryngeal nerve paralysis. Conclusions CLN metastasis in unilateral cN0 PTC patients was characterized with relation to sex, age, and lymph node density. Therefore prophylactic CLN dissection is necessary and safe for unilateral cN0 PTC patients.https://www.qk.sjtu.edu.cn/jscp/fileup/1007-9610/PDF/1658864436469-2121370401.pdf|papillary thyroid carcinoma|central compartment lymph node metastasis|metastatic lymph node density|braf v600e |
| spellingShingle | LIU Wei, WANG Cong, XUE Anwei, ZHAO Junjie, WANG Zhenglin Characteristics of central compartment lymph node metastasis in patients with unilateral cN0 papillary thyroid carcinoma and prophylactic dissection Waike lilun yu shijian |papillary thyroid carcinoma|central compartment lymph node metastasis|metastatic lymph node density|braf v600e |
| title | Characteristics of central compartment lymph node metastasis in patients with unilateral cN0 papillary thyroid carcinoma and prophylactic dissection |
| title_full | Characteristics of central compartment lymph node metastasis in patients with unilateral cN0 papillary thyroid carcinoma and prophylactic dissection |
| title_fullStr | Characteristics of central compartment lymph node metastasis in patients with unilateral cN0 papillary thyroid carcinoma and prophylactic dissection |
| title_full_unstemmed | Characteristics of central compartment lymph node metastasis in patients with unilateral cN0 papillary thyroid carcinoma and prophylactic dissection |
| title_short | Characteristics of central compartment lymph node metastasis in patients with unilateral cN0 papillary thyroid carcinoma and prophylactic dissection |
| title_sort | characteristics of central compartment lymph node metastasis in patients with unilateral cn0 papillary thyroid carcinoma and prophylactic dissection |
| topic | |papillary thyroid carcinoma|central compartment lymph node metastasis|metastatic lymph node density|braf v600e |
| url | https://www.qk.sjtu.edu.cn/jscp/fileup/1007-9610/PDF/1658864436469-2121370401.pdf |
| work_keys_str_mv | AT liuweiwangcongxueanweizhaojunjiewangzhenglin characteristicsofcentralcompartmentlymphnodemetastasisinpatientswithunilateralcn0papillarythyroidcarcinomaandprophylacticdissection |