A Study on the Relationship between Type 2 Diabetes and Taste Function in Patients with Good Glycemic Control
Type 2 diabetes mellitus (T2DM) has a very high impact on quality of life as it is characterized by disabling complications. There is little evidence about taste alterations in diabetes. Since many individual factors are involved in the onset of diabetes, the purpose of our study is to search a poss...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-04-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/12/4/1112 |
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| author | Sofia Pugnaloni Sonila Alia Margherita Mancini Vito Santoro Alice Di Paolo Rosa Anna Rabini Rosamaria Fiorini Jacopo Sabbatinelli Mara Fabri Laura Mazzanti Arianna Vignini |
| author_facet | Sofia Pugnaloni Sonila Alia Margherita Mancini Vito Santoro Alice Di Paolo Rosa Anna Rabini Rosamaria Fiorini Jacopo Sabbatinelli Mara Fabri Laura Mazzanti Arianna Vignini |
| author_sort | Sofia Pugnaloni |
| collection | DOAJ |
| description | Type 2 diabetes mellitus (T2DM) has a very high impact on quality of life as it is characterized by disabling complications. There is little evidence about taste alterations in diabetes. Since many individual factors are involved in the onset of diabetes, the purpose of our study is to search a possible link between diabetes and individual taste function. Thirty-two participants with T2DM and 32 volunteers without T2DM (healthy controls) were recruited. Four concentrations of each of the four basic tastes (sweet, sour, salty, bitter), and pure rapeseed oil and water, were applied with cotton pads to the protruded tongue, immediately posterior to its first third, either to the left or right side. The results showed significant differences between groups in the ability to recognize sour, bitter, sweet, and water. Taste scores were lower in subjects with T2DM than in healthy controls, and an age-related decline in taste function was found. The taste function reduction associated with T2DM was not related to gender, disease duration, and glycemic control. In conclusion, it can be hypothesized that a general alteration of taste function can lead patients with type 2 diabetes to search for foods richer in sugars, as in a vicious circle, thus decreasing the likelihood of remission of diabetes mellitus. |
| first_indexed | 2024-03-10T20:24:50Z |
| format | Article |
| id | doaj.art-17515fd17cd9491cac0b53fe153965e6 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-10T20:24:50Z |
| publishDate | 2020-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-17515fd17cd9491cac0b53fe153965e62023-11-19T21:50:18ZengMDPI AGNutrients2072-66432020-04-01124111210.3390/nu12041112A Study on the Relationship between Type 2 Diabetes and Taste Function in Patients with Good Glycemic ControlSofia Pugnaloni0Sonila Alia1Margherita Mancini2Vito Santoro3Alice Di Paolo4Rosa Anna Rabini5Rosamaria Fiorini6Jacopo Sabbatinelli7Mara Fabri8Laura Mazzanti9Arianna Vignini10Department of Clinical Sciences, Section of Biochemistry, Biology and Physics, Università Politecnica delle Marche, Via Tronto 10/A, 60126 Ancona, ItalyDepartment of Clinical Sciences, Section of Biochemistry, Biology and Physics, Università Politecnica delle Marche, Via Tronto 10/A, 60126 Ancona, ItalyDepartment of Clinical Sciences, School of Specialization in Clinical Nutrition, Università Politecnica delle Marche, Via Tronto 10/A, 60126 Ancona, ItalyDepartment of Clinical Sciences, School of Specialization in Clinical Nutrition, Università Politecnica delle Marche, Via Tronto 10/A, 60126 Ancona, ItalyDepartment of Clinical Sciences, Section of Biochemistry, Biology and Physics, Università Politecnica delle Marche, Via Tronto 10/A, 60126 Ancona, ItalyDiabetology Department, IRCCS INRCA, Via della Montagnola 81, 60127 Ancona, ItalyDepartment of Life and Environmental Sciences, Università Politecnica delle Marche, Via Brecce Bianche, 60131 Ancona, ItalyDepartment of Clinical Sciences, Section of Biochemistry, Biology and Physics, Università Politecnica delle Marche, Via Tronto 10/A, 60126 Ancona, ItalyDepartment of Experimental and Clinical Medicine, Università Politecnica delle Marche, Via Tronto 10/A, 60126 Ancona, ItalyDepartment of Clinical Sciences, Section of Biochemistry, Biology and Physics, Università Politecnica delle Marche, Via Tronto 10/A, 60126 Ancona, ItalyDepartment of Clinical Sciences, Section of Biochemistry, Biology and Physics, Università Politecnica delle Marche, Via Tronto 10/A, 60126 Ancona, ItalyType 2 diabetes mellitus (T2DM) has a very high impact on quality of life as it is characterized by disabling complications. There is little evidence about taste alterations in diabetes. Since many individual factors are involved in the onset of diabetes, the purpose of our study is to search a possible link between diabetes and individual taste function. Thirty-two participants with T2DM and 32 volunteers without T2DM (healthy controls) were recruited. Four concentrations of each of the four basic tastes (sweet, sour, salty, bitter), and pure rapeseed oil and water, were applied with cotton pads to the protruded tongue, immediately posterior to its first third, either to the left or right side. The results showed significant differences between groups in the ability to recognize sour, bitter, sweet, and water. Taste scores were lower in subjects with T2DM than in healthy controls, and an age-related decline in taste function was found. The taste function reduction associated with T2DM was not related to gender, disease duration, and glycemic control. In conclusion, it can be hypothesized that a general alteration of taste function can lead patients with type 2 diabetes to search for foods richer in sugars, as in a vicious circle, thus decreasing the likelihood of remission of diabetes mellitus.https://www.mdpi.com/2072-6643/12/4/1112diabetestaste functiongenderfood preferences |
| spellingShingle | Sofia Pugnaloni Sonila Alia Margherita Mancini Vito Santoro Alice Di Paolo Rosa Anna Rabini Rosamaria Fiorini Jacopo Sabbatinelli Mara Fabri Laura Mazzanti Arianna Vignini A Study on the Relationship between Type 2 Diabetes and Taste Function in Patients with Good Glycemic Control Nutrients diabetes taste function gender food preferences |
| title | A Study on the Relationship between Type 2 Diabetes and Taste Function in Patients with Good Glycemic Control |
| title_full | A Study on the Relationship between Type 2 Diabetes and Taste Function in Patients with Good Glycemic Control |
| title_fullStr | A Study on the Relationship between Type 2 Diabetes and Taste Function in Patients with Good Glycemic Control |
| title_full_unstemmed | A Study on the Relationship between Type 2 Diabetes and Taste Function in Patients with Good Glycemic Control |
| title_short | A Study on the Relationship between Type 2 Diabetes and Taste Function in Patients with Good Glycemic Control |
| title_sort | study on the relationship between type 2 diabetes and taste function in patients with good glycemic control |
| topic | diabetes taste function gender food preferences |
| url | https://www.mdpi.com/2072-6643/12/4/1112 |
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