Evolutionary Steps in the Emergence of Life Deduced from the Bottom-Up Approach and GADV Hypothesis (Top-Down Approach)

It is no doubt quite difficult to solve the riddle of the origin of life. So, firstly, I would like to point out the kinds of obstacles there are in solving this riddle and how we should tackle these difficult problems, reviewing the studies that have been conducted so far. After that, I will propos...

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Main Author: Kenji Ikehara
Format: Article
Language:English
Published: MDPI AG 2016-01-01
Series:Life
Subjects:
Online Access:http://www.mdpi.com/2075-1729/6/1/6
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author Kenji Ikehara
author_facet Kenji Ikehara
author_sort Kenji Ikehara
collection DOAJ
description It is no doubt quite difficult to solve the riddle of the origin of life. So, firstly, I would like to point out the kinds of obstacles there are in solving this riddle and how we should tackle these difficult problems, reviewing the studies that have been conducted so far. After that, I will propose that the consecutive evolutionary steps in a timeline can be rationally deduced by using a common event as a juncture, which is obtained by two counter-directional approaches: one is the bottom-up approach through which many researchers have studied the origin of life, and the other is the top-down approach, through which I established the [GADV]-protein world hypothesis or GADV hypothesis on the origin of life starting from a study on the formation of entirely new genes in extant microorganisms. Last, I will describe the probable evolutionary process from the formation of Earth to the emergence of life, which was deduced by using a common event—the establishment of the first genetic code encoding [GADV]-amino acids—as a juncture for the results obtained from the two approaches.
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spelling doaj.art-1756575215aa4a9693e95987e7c03d222022-12-22T01:56:44ZengMDPI AGLife2075-17292016-01-0161610.3390/life6010006life6010006Evolutionary Steps in the Emergence of Life Deduced from the Bottom-Up Approach and GADV Hypothesis (Top-Down Approach)Kenji Ikehara0G & L Kyosei Institute, Keihannna Labo-401, Hikaridai 1-7, Seika-cho, Sorakugun, Kyoto 619-0237, JapanIt is no doubt quite difficult to solve the riddle of the origin of life. So, firstly, I would like to point out the kinds of obstacles there are in solving this riddle and how we should tackle these difficult problems, reviewing the studies that have been conducted so far. After that, I will propose that the consecutive evolutionary steps in a timeline can be rationally deduced by using a common event as a juncture, which is obtained by two counter-directional approaches: one is the bottom-up approach through which many researchers have studied the origin of life, and the other is the top-down approach, through which I established the [GADV]-protein world hypothesis or GADV hypothesis on the origin of life starting from a study on the formation of entirely new genes in extant microorganisms. Last, I will describe the probable evolutionary process from the formation of Earth to the emergence of life, which was deduced by using a common event—the establishment of the first genetic code encoding [GADV]-amino acids—as a juncture for the results obtained from the two approaches.http://www.mdpi.com/2075-1729/6/1/6origin of life[GADV]-protein worldGADV hypothesispseudo-replicationprotein 0th-order structure
spellingShingle Kenji Ikehara
Evolutionary Steps in the Emergence of Life Deduced from the Bottom-Up Approach and GADV Hypothesis (Top-Down Approach)
Life
origin of life
[GADV]-protein world
GADV hypothesis
pseudo-replication
protein 0th-order structure
title Evolutionary Steps in the Emergence of Life Deduced from the Bottom-Up Approach and GADV Hypothesis (Top-Down Approach)
title_full Evolutionary Steps in the Emergence of Life Deduced from the Bottom-Up Approach and GADV Hypothesis (Top-Down Approach)
title_fullStr Evolutionary Steps in the Emergence of Life Deduced from the Bottom-Up Approach and GADV Hypothesis (Top-Down Approach)
title_full_unstemmed Evolutionary Steps in the Emergence of Life Deduced from the Bottom-Up Approach and GADV Hypothesis (Top-Down Approach)
title_short Evolutionary Steps in the Emergence of Life Deduced from the Bottom-Up Approach and GADV Hypothesis (Top-Down Approach)
title_sort evolutionary steps in the emergence of life deduced from the bottom up approach and gadv hypothesis top down approach
topic origin of life
[GADV]-protein world
GADV hypothesis
pseudo-replication
protein 0th-order structure
url http://www.mdpi.com/2075-1729/6/1/6
work_keys_str_mv AT kenjiikehara evolutionarystepsintheemergenceoflifededucedfromthebottomupapproachandgadvhypothesistopdownapproach