Influence of polygenic risk scores for schizophrenia and resilience on the cognition of individuals at-risk for psychosis
Abstract Cognitive impairment is a core feature of schizophrenia which precedes the onset of full psychotic symptoms, even in the ultra-high-risk stage (UHR). Polygenic risk scores (PRS) can be computed for many psychiatric disorders and phenotyping traits, including scores for resilience. We explor...
Main Authors: | Qin He, Célia Jantac Mam-Lam-Fook, Julie Chaignaud, Charlotte Danset-Alexandre, Anton Iftimovici, Johanna Gradels Hauguel, Gabrielle Houle, Calwing Liao, ICAAR study group, Patrick A. Dion, Guy A. Rouleau, Oussama Kebir, Marie-Odile Krebs, Boris Chaumette |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-10-01
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Series: | Translational Psychiatry |
Online Access: | https://doi.org/10.1038/s41398-021-01624-z |
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