Different kinds of acupuncture treatments for knee osteoarthritis: a multicentre, randomized controlled trial
Abstract Introduction Knee osteoarthritis (KOA) is a chronic disease with symptoms of persistent pain or resting pain, joint stiffness, numbness, limitation of activity and even disability, with significant associated costs and effects on individuals’ life quality. The use of acupuncture for the man...
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| Format: | Article |
| Language: | English |
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BMC
2020-03-01
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| Series: | Trials |
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| Online Access: | http://link.springer.com/article/10.1186/s13063-019-4034-8 |
| _version_ | 1824012023679156224 |
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| author | Qifei Zhang Jianqiao Fang Lifang Chen Jiayao Wu Jing Ni Fang Liu Jing Sun |
| author_facet | Qifei Zhang Jianqiao Fang Lifang Chen Jiayao Wu Jing Ni Fang Liu Jing Sun |
| author_sort | Qifei Zhang |
| collection | DOAJ |
| description | Abstract Introduction Knee osteoarthritis (KOA) is a chronic disease with symptoms of persistent pain or resting pain, joint stiffness, numbness, limitation of activity and even disability, with significant associated costs and effects on individuals’ life quality. The use of acupuncture for the management of chronic pain is receiving increasing recognition from both the public and professionals. The aim of this study is to identify the effects of three commonly used acupuncture treatments for KOA. Methods/analysis In a prospective trial involving six hospitals in Zhejiang Province (China), 360 patients with KOA will be included. Eligible patients will be randomized into six groups: Acupuncture, Electro-acupuncture, Mild moxibustion, Warm-needling, Sham acupuncture and Celebrex treatment. Twelve treatment sessions will be performed over a 4-week period. The primary outcome will be the visual analogue scale and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) function scores (the average of the past 3 days) at weeks 2 and 4 and at 3-month and 6-month follow-up. Secondary outcome measures will be as follows: the WOMAC pain score and WOMAC stiffness score (the average of the past 3 days); the Physical Activity Scale of the Elderly (PASE); knee joint swelling measurement; the WHO Quality Of Life-BREF (WHOQOL-BREF) life quality scale; and the incidence of adverse events. Trial registration ClinicalTrials.gov, NCT03563690 . Registered on 2rd July 2018. |
| first_indexed | 2024-12-18T21:43:01Z |
| format | Article |
| id | doaj.art-175d5e6cb38e40ce8e29cf7eef4a6480 |
| institution | Directory Open Access Journal |
| issn | 1745-6215 |
| language | English |
| last_indexed | 2024-12-18T21:43:01Z |
| publishDate | 2020-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Trials |
| spelling | doaj.art-175d5e6cb38e40ce8e29cf7eef4a64802022-12-21T20:50:45ZengBMCTrials1745-62152020-03-0121111010.1186/s13063-019-4034-8Different kinds of acupuncture treatments for knee osteoarthritis: a multicentre, randomized controlled trialQifei Zhang0Jianqiao Fang1Lifang Chen2Jiayao Wu3Jing Ni4Fang Liu5Jing Sun6The Third Clinical Medical College, Zhejiang Chinese Medical UniversityDepartment of Acupuncture, The Third Affiliated Hospital of Zhejiang Chinese Medical UniversityDepartment of Acupuncture, Third Affiliated Hospital of Zhejiang Traditional Chinese Medical UniversityDepartment of Acupuncture, The Third Affiliated Hospital of Zhejiang Chinese Medical UniversityDepartment of Acupuncture, The Third Affiliated Hospital of Zhejiang Chinese Medical UniversityDepartment of Acupuncture, Hangzhou Red Cross HospitalDepartment of Acupuncture, Third Affiliated Hospital of Zhejiang Traditional Chinese Medical UniversityAbstract Introduction Knee osteoarthritis (KOA) is a chronic disease with symptoms of persistent pain or resting pain, joint stiffness, numbness, limitation of activity and even disability, with significant associated costs and effects on individuals’ life quality. The use of acupuncture for the management of chronic pain is receiving increasing recognition from both the public and professionals. The aim of this study is to identify the effects of three commonly used acupuncture treatments for KOA. Methods/analysis In a prospective trial involving six hospitals in Zhejiang Province (China), 360 patients with KOA will be included. Eligible patients will be randomized into six groups: Acupuncture, Electro-acupuncture, Mild moxibustion, Warm-needling, Sham acupuncture and Celebrex treatment. Twelve treatment sessions will be performed over a 4-week period. The primary outcome will be the visual analogue scale and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) function scores (the average of the past 3 days) at weeks 2 and 4 and at 3-month and 6-month follow-up. Secondary outcome measures will be as follows: the WOMAC pain score and WOMAC stiffness score (the average of the past 3 days); the Physical Activity Scale of the Elderly (PASE); knee joint swelling measurement; the WHO Quality Of Life-BREF (WHOQOL-BREF) life quality scale; and the incidence of adverse events. Trial registration ClinicalTrials.gov, NCT03563690 . Registered on 2rd July 2018.http://link.springer.com/article/10.1186/s13063-019-4034-8AcupunctureKnee osteoarthritisElectro-acupunctureWarm-needlingSham acupunctureMild moxibustion |
| spellingShingle | Qifei Zhang Jianqiao Fang Lifang Chen Jiayao Wu Jing Ni Fang Liu Jing Sun Different kinds of acupuncture treatments for knee osteoarthritis: a multicentre, randomized controlled trial Trials Acupuncture Knee osteoarthritis Electro-acupuncture Warm-needling Sham acupuncture Mild moxibustion |
| title | Different kinds of acupuncture treatments for knee osteoarthritis: a multicentre, randomized controlled trial |
| title_full | Different kinds of acupuncture treatments for knee osteoarthritis: a multicentre, randomized controlled trial |
| title_fullStr | Different kinds of acupuncture treatments for knee osteoarthritis: a multicentre, randomized controlled trial |
| title_full_unstemmed | Different kinds of acupuncture treatments for knee osteoarthritis: a multicentre, randomized controlled trial |
| title_short | Different kinds of acupuncture treatments for knee osteoarthritis: a multicentre, randomized controlled trial |
| title_sort | different kinds of acupuncture treatments for knee osteoarthritis a multicentre randomized controlled trial |
| topic | Acupuncture Knee osteoarthritis Electro-acupuncture Warm-needling Sham acupuncture Mild moxibustion |
| url | http://link.springer.com/article/10.1186/s13063-019-4034-8 |
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