3C-BASED METHODS FOR 3D GENOME ORGANIZATION ANALYSIS
The 3D organization of an eukaryotic genome plays an important role in nuclear gene expression. Until recently, studies of this organization were limited by light microscopy and electron microscopy methods. The development of chromosome conformation capture (3С) methods allowed studying genome-wide...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders
2014-12-01
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| Series: | Вавиловский журнал генетики и селекции |
| Subjects: | |
| Online Access: | https://vavilov.elpub.ru/jour/article/view/85 |
| _version_ | 1797214198345760768 |
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| author | N. R. Battulin V. S. Fishman Yu. L. Orlov A. G. Menzorov D. A. Afonnikov O. L. Serov |
| author_facet | N. R. Battulin V. S. Fishman Yu. L. Orlov A. G. Menzorov D. A. Afonnikov O. L. Serov |
| author_sort | N. R. Battulin |
| collection | DOAJ |
| description | The 3D organization of an eukaryotic genome plays an important role in nuclear gene expression. Until recently, studies of this organization were limited by light microscopy and electron microscopy methods. The development of chromosome conformation capture (3С) methods allowed studying genome-wide chromosomal contacts by using only molecular methods. Nowadays, numerous 3C-based methods have been developed to reconstruct the 3D organization of eukaryotic genomes. |
| first_indexed | 2024-03-07T16:08:47Z |
| format | Article |
| id | doaj.art-175e7a583d084090892d9aabe1640765 |
| institution | Directory Open Access Journal |
| issn | 2500-3259 |
| language | English |
| last_indexed | 2024-04-24T11:10:22Z |
| publishDate | 2014-12-01 |
| publisher | Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders |
| record_format | Article |
| series | Вавиловский журнал генетики и селекции |
| spelling | doaj.art-175e7a583d084090892d9aabe16407652024-04-11T15:30:52ZengSiberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and BreedersВавиловский журнал генетики и селекции2500-32592014-12-01164/2872878693C-BASED METHODS FOR 3D GENOME ORGANIZATION ANALYSISN. R. Battulin0V. S. Fishman1Yu. L. Orlov2A. G. Menzorov3D. A. Afonnikov4O. L. Serov5Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia Novosibirsk State University, Novosibirsk, RussiaInstitute of Cytology and Genetics SB RAS, Novosibirsk, Russia Novosibirsk State University, Novosibirsk, RussiaInstitute of Cytology and Genetics SB RAS, Novosibirsk, Russia Novosibirsk State University, Novosibirsk, RussiaInstitute of Cytology and Genetics SB RAS, Novosibirsk, Russia Novosibirsk State University, Novosibirsk, RussiaInstitute of Cytology and Genetics SB RAS, Novosibirsk, Russia Novosibirsk State University, Novosibirsk, RussiaInstitute of Cytology and Genetics SB RAS, Novosibirsk, Russia Novosibirsk State University, Novosibirsk, RussiaThe 3D organization of an eukaryotic genome plays an important role in nuclear gene expression. Until recently, studies of this organization were limited by light microscopy and electron microscopy methods. The development of chromosome conformation capture (3С) methods allowed studying genome-wide chromosomal contacts by using only molecular methods. Nowadays, numerous 3C-based methods have been developed to reconstruct the 3D organization of eukaryotic genomes.https://vavilov.elpub.ru/jour/article/view/853d genome organization, 3chi-ctopological domains |
| spellingShingle | N. R. Battulin V. S. Fishman Yu. L. Orlov A. G. Menzorov D. A. Afonnikov O. L. Serov 3C-BASED METHODS FOR 3D GENOME ORGANIZATION ANALYSIS Вавиловский журнал генетики и селекции 3d genome organization , 3c hi-c topological domains |
| title | 3C-BASED METHODS FOR 3D GENOME ORGANIZATION ANALYSIS |
| title_full | 3C-BASED METHODS FOR 3D GENOME ORGANIZATION ANALYSIS |
| title_fullStr | 3C-BASED METHODS FOR 3D GENOME ORGANIZATION ANALYSIS |
| title_full_unstemmed | 3C-BASED METHODS FOR 3D GENOME ORGANIZATION ANALYSIS |
| title_short | 3C-BASED METHODS FOR 3D GENOME ORGANIZATION ANALYSIS |
| title_sort | 3c based methods for 3d genome organization analysis |
| topic | 3d genome organization , 3c hi-c topological domains |
| url | https://vavilov.elpub.ru/jour/article/view/85 |
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