The Drug Coated Balloon-Only Strategy for Treatment of de Novo Left Main Coronary Artery Bifurcation Lesion: Stentless Strategy
The study aimed to evaluate the efficacy and safety of drug coated balloon-only strategy (DCB-only) in the treatment of de novo left main coronary artery (LM) bifurcation lesions. 85 patients were enrolled in this study and classified them into two groups: DCB-only group (n = 36) and DES group (n = ...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2022-08-01
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| Series: | Clinical and Applied Thrombosis/Hemostasis |
| Online Access: | https://doi.org/10.1177/10760296221118489 |
| _version_ | 1811308980654309376 |
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| author | Hengdao Liu Yanyan Zhao Yang Lu Shilong Zhou Yubin Zhang Junwei Zhao Huilin Yang Junhui Xing Ruihan Feng XiaoFei Xue Hailong Tao Ruipeng Song Heping Gu |
| author_facet | Hengdao Liu Yanyan Zhao Yang Lu Shilong Zhou Yubin Zhang Junwei Zhao Huilin Yang Junhui Xing Ruihan Feng XiaoFei Xue Hailong Tao Ruipeng Song Heping Gu |
| author_sort | Hengdao Liu |
| collection | DOAJ |
| description | The study aimed to evaluate the efficacy and safety of drug coated balloon-only strategy (DCB-only) in the treatment of de novo left main coronary artery (LM) bifurcation lesions. 85 patients were enrolled in this study and classified them into two groups: DCB-only group (n = 36) and DES group (n = 49). The MLD of target vessels was measured before and immediately after percutaneous coronary intervention (PCI) and late luminal loss (LLL) were also calculated. And the occurrence of major adverse cardiovascular events (MACE) was also evaluated. Compared with that before PCI, the MLD of target lesions significantly increased immediately after PCI ( P < .05) and no MACE was recorded during the perioperative period both in two groups. The MLD at follow-up was significantly higher than that before both DCB and DES treatment. Compared with the DES group, the MLD of the DCB group was smaller than immediately after PCI in the LM and LAD ( P < .05). The LLL of LAD in DCB group was smaller than that in DES group ( P < .05). There was no significant difference in the incidence of luminal restenosis at the target lesion between the two groups, and no significant difference in the incidence of MACE ( P > .05). The use of DCB-only to treat de novo LM bifurcation lesions is effective and relatively safe, which provides new ideas for the treatment of LM coronary artery bifurcation lesions in the future. |
| first_indexed | 2024-04-13T09:34:05Z |
| format | Article |
| id | doaj.art-176ad7eacc8141f6b4e79c8b4105e971 |
| institution | Directory Open Access Journal |
| issn | 1938-2723 |
| language | English |
| last_indexed | 2024-04-13T09:34:05Z |
| publishDate | 2022-08-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Clinical and Applied Thrombosis/Hemostasis |
| spelling | doaj.art-176ad7eacc8141f6b4e79c8b4105e9712022-12-22T02:52:09ZengSAGE PublishingClinical and Applied Thrombosis/Hemostasis1938-27232022-08-012810.1177/10760296221118489The Drug Coated Balloon-Only Strategy for Treatment of de Novo Left Main Coronary Artery Bifurcation Lesion: Stentless StrategyHengdao Liu0Yanyan Zhao1Yang Lu2Shilong Zhou3Yubin Zhang4Junwei Zhao5Huilin Yang6Junhui Xing7Ruihan Feng8XiaoFei Xue9Hailong Tao10Ruipeng Song11Heping Gu12 Department of Cardiology, , Zhengzhou, Henan, China Department of Cardiology, , Zhengzhou, Henan, China Department of Emergency, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China Department of Cardiology, , Zhengzhou, Henan, China Department of Cardiology, , Zhengzhou, Henan, China Department of Cardiology, Yexian People's Hospital, Pingdingshan, Henan, China Department of Cardiology, Nanle people's Hospital, Puyang, Henan, China Department of Cardiology, , Zhengzhou, Henan, China Department of Cardiology, Xinxiang Central Hospital, Xinxiang, Henan, China Department of Cardiology, , Zhengzhou, Henan, China Department of Cardiology, , Zhengzhou, Henan, China Department of Endocrinology, The Third People's Provincial Hospital of Henan Province, Zhengzhou, Henan, China Department of Cardiology, , Zhengzhou, Henan, ChinaThe study aimed to evaluate the efficacy and safety of drug coated balloon-only strategy (DCB-only) in the treatment of de novo left main coronary artery (LM) bifurcation lesions. 85 patients were enrolled in this study and classified them into two groups: DCB-only group (n = 36) and DES group (n = 49). The MLD of target vessels was measured before and immediately after percutaneous coronary intervention (PCI) and late luminal loss (LLL) were also calculated. And the occurrence of major adverse cardiovascular events (MACE) was also evaluated. Compared with that before PCI, the MLD of target lesions significantly increased immediately after PCI ( P < .05) and no MACE was recorded during the perioperative period both in two groups. The MLD at follow-up was significantly higher than that before both DCB and DES treatment. Compared with the DES group, the MLD of the DCB group was smaller than immediately after PCI in the LM and LAD ( P < .05). The LLL of LAD in DCB group was smaller than that in DES group ( P < .05). There was no significant difference in the incidence of luminal restenosis at the target lesion between the two groups, and no significant difference in the incidence of MACE ( P > .05). The use of DCB-only to treat de novo LM bifurcation lesions is effective and relatively safe, which provides new ideas for the treatment of LM coronary artery bifurcation lesions in the future.https://doi.org/10.1177/10760296221118489 |
| spellingShingle | Hengdao Liu Yanyan Zhao Yang Lu Shilong Zhou Yubin Zhang Junwei Zhao Huilin Yang Junhui Xing Ruihan Feng XiaoFei Xue Hailong Tao Ruipeng Song Heping Gu The Drug Coated Balloon-Only Strategy for Treatment of de Novo Left Main Coronary Artery Bifurcation Lesion: Stentless Strategy Clinical and Applied Thrombosis/Hemostasis |
| title | The Drug Coated Balloon-Only Strategy for Treatment of de Novo Left Main Coronary Artery Bifurcation Lesion: Stentless Strategy |
| title_full | The Drug Coated Balloon-Only Strategy for Treatment of de Novo Left Main Coronary Artery Bifurcation Lesion: Stentless Strategy |
| title_fullStr | The Drug Coated Balloon-Only Strategy for Treatment of de Novo Left Main Coronary Artery Bifurcation Lesion: Stentless Strategy |
| title_full_unstemmed | The Drug Coated Balloon-Only Strategy for Treatment of de Novo Left Main Coronary Artery Bifurcation Lesion: Stentless Strategy |
| title_short | The Drug Coated Balloon-Only Strategy for Treatment of de Novo Left Main Coronary Artery Bifurcation Lesion: Stentless Strategy |
| title_sort | drug coated balloon only strategy for treatment of de novo left main coronary artery bifurcation lesion stentless strategy |
| url | https://doi.org/10.1177/10760296221118489 |
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