OSTEOARTHRITIS: CURRENT CLINICAL CONCEPT AND SOME PROMISING THERAPEUTIC APPROACHES
In recent years, there has been a trend toward changing the clinical concept of osteoarthritis (OA). This disease has been considered as an age-related disease and the long-term result of a current pathological process for a very long time. However, many experts are now inclined to consider it neces...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
IMA PRESS LLC
2018-03-01
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| Series: | Научно-практическая ревматология |
| Subjects: | |
| Online Access: | https://rsp.mediar-press.net/rsp/article/view/2502 |
| _version_ | 1797862629916540928 |
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| author | A. E. Karateev A. M. Lila |
| author_facet | A. E. Karateev A. M. Lila |
| author_sort | A. E. Karateev |
| collection | DOAJ |
| description | In recent years, there has been a trend toward changing the clinical concept of osteoarthritis (OA). This disease has been considered as an age-related disease and the long-term result of a current pathological process for a very long time. However, many experts are now inclined to consider it necessary to identify the early, pre-X-ray stage of OA, when adequate treatment may not only halt the progression, but also achieve the regression of joint structural changes. This review deals with a number of pathogenetic and clinical aspects of the early stages of OA, which are important for timely diagnosis and pathogenetic therapy choice. It also considers some therapeutic approaches, both a "classic" and recently actively discussed methods for using platelet-rich plasma and autologous chondrocyte transplantation. |
| first_indexed | 2024-04-09T22:23:41Z |
| format | Article |
| id | doaj.art-176b1df1d13e4b35bbf27f48aee77de3 |
| institution | Directory Open Access Journal |
| issn | 1995-4484 1995-4492 |
| language | Russian |
| last_indexed | 2024-04-09T22:23:41Z |
| publishDate | 2018-03-01 |
| publisher | IMA PRESS LLC |
| record_format | Article |
| series | Научно-практическая ревматология |
| spelling | doaj.art-176b1df1d13e4b35bbf27f48aee77de32023-03-22T13:45:53ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922018-03-01561708110.14412/1995-4484-2018-70-812310OSTEOARTHRITIS: CURRENT CLINICAL CONCEPT AND SOME PROMISING THERAPEUTIC APPROACHESA. E. Karateev0A. M. Lila1V.A.Nasonova Research Institute of Rheumatology.V.A.Nasonova Research Institute of Rheumatology.In recent years, there has been a trend toward changing the clinical concept of osteoarthritis (OA). This disease has been considered as an age-related disease and the long-term result of a current pathological process for a very long time. However, many experts are now inclined to consider it necessary to identify the early, pre-X-ray stage of OA, when adequate treatment may not only halt the progression, but also achieve the regression of joint structural changes. This review deals with a number of pathogenetic and clinical aspects of the early stages of OA, which are important for timely diagnosis and pathogenetic therapy choice. It also considers some therapeutic approaches, both a "classic" and recently actively discussed methods for using platelet-rich plasma and autologous chondrocyte transplantation.https://rsp.mediar-press.net/rsp/article/view/2502osteoarthritisearly osteoarthritispathogenesistreatmentplatelet-rich plasmaautologous chondrocyte transplantation |
| spellingShingle | A. E. Karateev A. M. Lila OSTEOARTHRITIS: CURRENT CLINICAL CONCEPT AND SOME PROMISING THERAPEUTIC APPROACHES Научно-практическая ревматология osteoarthritis early osteoarthritis pathogenesis treatment platelet-rich plasma autologous chondrocyte transplantation |
| title | OSTEOARTHRITIS: CURRENT CLINICAL CONCEPT AND SOME PROMISING THERAPEUTIC APPROACHES |
| title_full | OSTEOARTHRITIS: CURRENT CLINICAL CONCEPT AND SOME PROMISING THERAPEUTIC APPROACHES |
| title_fullStr | OSTEOARTHRITIS: CURRENT CLINICAL CONCEPT AND SOME PROMISING THERAPEUTIC APPROACHES |
| title_full_unstemmed | OSTEOARTHRITIS: CURRENT CLINICAL CONCEPT AND SOME PROMISING THERAPEUTIC APPROACHES |
| title_short | OSTEOARTHRITIS: CURRENT CLINICAL CONCEPT AND SOME PROMISING THERAPEUTIC APPROACHES |
| title_sort | osteoarthritis current clinical concept and some promising therapeutic approaches |
| topic | osteoarthritis early osteoarthritis pathogenesis treatment platelet-rich plasma autologous chondrocyte transplantation |
| url | https://rsp.mediar-press.net/rsp/article/view/2502 |
| work_keys_str_mv | AT aekarateev osteoarthritiscurrentclinicalconceptandsomepromisingtherapeuticapproaches AT amlila osteoarthritiscurrentclinicalconceptandsomepromisingtherapeuticapproaches |