Adipose Tissue, Metabolic Syndrome, and Non-Alcoholic Fatty Liver Disease – A Short Review
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease globally, and it is expected to rise even further as a result of the increase in obesity and related risk factors. This short review summarises current evidence on the role of adipose tissue and insulin resistance in...
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| Format: | Article |
| Language: | English |
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European Medical Journal
2014-05-01
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| Series: | European Medical Journal Hepatology |
| Subjects: | |
| Online Access: | http://emjreviews.com/wp-content/uploads/ADIPOSE-TISSUE-METABOLIC-SYNDROME-AND-NON-ALCOHOLIC-FATTY-LIVER-DISEASE-A-SHORT-REVIEW.pdf |
| _version_ | 1828259173062672384 |
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| author | Panayiotis Kouis Despina Pampaka Andrie G Panayiotou |
| author_facet | Panayiotis Kouis Despina Pampaka Andrie G Panayiotou |
| author_sort | Panayiotis Kouis |
| collection | DOAJ |
| description | Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease globally, and it is expected to rise even further as a result of the increase in obesity and related risk factors. This short review summarises current evidence on the role of adipose tissue and insulin resistance in NAFLD and the interrelationship between NAFLD and the metabolic syndrome (MetS), considering central adiposity is a major feature of both the MetS and NAFLD, and that NAFLD has been previously described as the hepatic manifestation of the MetS. In addition, genetic studies of NAFLD with relation to adiposity and insulin resistance are reviewed, and up-to-date diagnostic and therapeutic tools are also discussed. |
| first_indexed | 2024-04-13T03:04:56Z |
| format | Article |
| id | doaj.art-176b4b6dd4784ef3afe1f21d432480c9 |
| institution | Directory Open Access Journal |
| issn | 2053-4221 |
| language | English |
| last_indexed | 2024-04-13T03:04:56Z |
| publishDate | 2014-05-01 |
| publisher | European Medical Journal |
| record_format | Article |
| series | European Medical Journal Hepatology |
| spelling | doaj.art-176b4b6dd4784ef3afe1f21d432480c92022-12-22T03:05:17ZengEuropean Medical JournalEuropean Medical Journal Hepatology2053-42212014-05-01216270Adipose Tissue, Metabolic Syndrome, and Non-Alcoholic Fatty Liver Disease – A Short ReviewPanayiotis Kouis0Despina Pampaka1Andrie G Panayiotou2Cyprus International Institute for Environmental and Public Health in association with the Harvard School of Public Health, Cyprus University of Technology, Limassol, CyprusCyprus International Institute for Environmental and Public Health in association with the Harvard School of Public Health, Cyprus University of Technology, Limassol, CyprusCyprus International Institute for Environmental and Public Health in association with the Harvard School of Public Health, Cyprus University of Technology, Limassol, CyprusNon-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease globally, and it is expected to rise even further as a result of the increase in obesity and related risk factors. This short review summarises current evidence on the role of adipose tissue and insulin resistance in NAFLD and the interrelationship between NAFLD and the metabolic syndrome (MetS), considering central adiposity is a major feature of both the MetS and NAFLD, and that NAFLD has been previously described as the hepatic manifestation of the MetS. In addition, genetic studies of NAFLD with relation to adiposity and insulin resistance are reviewed, and up-to-date diagnostic and therapeutic tools are also discussed.http://emjreviews.com/wp-content/uploads/ADIPOSE-TISSUE-METABOLIC-SYNDROME-AND-NON-ALCOHOLIC-FATTY-LIVER-DISEASE-A-SHORT-REVIEW.pdfadipose tissuegenetics of NAFLD.insulin resistanceMetabolic SyndromeNAFLD |
| spellingShingle | Panayiotis Kouis Despina Pampaka Andrie G Panayiotou Adipose Tissue, Metabolic Syndrome, and Non-Alcoholic Fatty Liver Disease – A Short Review European Medical Journal Hepatology adipose tissue genetics of NAFLD. insulin resistance Metabolic Syndrome NAFLD |
| title | Adipose Tissue, Metabolic Syndrome, and Non-Alcoholic Fatty Liver Disease – A Short Review |
| title_full | Adipose Tissue, Metabolic Syndrome, and Non-Alcoholic Fatty Liver Disease – A Short Review |
| title_fullStr | Adipose Tissue, Metabolic Syndrome, and Non-Alcoholic Fatty Liver Disease – A Short Review |
| title_full_unstemmed | Adipose Tissue, Metabolic Syndrome, and Non-Alcoholic Fatty Liver Disease – A Short Review |
| title_short | Adipose Tissue, Metabolic Syndrome, and Non-Alcoholic Fatty Liver Disease – A Short Review |
| title_sort | adipose tissue metabolic syndrome and non alcoholic fatty liver disease a short review |
| topic | adipose tissue genetics of NAFLD. insulin resistance Metabolic Syndrome NAFLD |
| url | http://emjreviews.com/wp-content/uploads/ADIPOSE-TISSUE-METABOLIC-SYNDROME-AND-NON-ALCOHOLIC-FATTY-LIVER-DISEASE-A-SHORT-REVIEW.pdf |
| work_keys_str_mv | AT panayiotiskouis adiposetissuemetabolicsyndromeandnonalcoholicfattyliverdiseaseashortreview AT despinapampaka adiposetissuemetabolicsyndromeandnonalcoholicfattyliverdiseaseashortreview AT andriegpanayiotou adiposetissuemetabolicsyndromeandnonalcoholicfattyliverdiseaseashortreview |