Cerebellar Purkinje cells incorporate immunoglobulins and immunotoxins in vitro: implications for human neurological disease and immunotherapeutics

Cerebellar Purkinje cells incorporate immunoglobulins and immunotoxins in vitro: implications for human neurological disease and immunotherapeutics

<p>Abstract</p> <p>Background</p> <p>Immunoglobulin G (IgG) antibodies reactive with intracellular neuronal proteins have been described in paraneoplastic and other autoimmune disorders. Because neurons have been thought impermeable to immunoglobulins, however, such ant...

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Bibliographic Details
Main Authors: Rose John W, Clawson Susan A, Hill Kenneth E, Carlson Noel G, Greenlee John E
Format: Article
Language:English
Published: BMC 2009-10-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/6/1/31

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