Methylation at global LINE-1 repeats in human blood are affected by gender but not by age or natural hormone cycles.

Methylation at global LINE-1 repeats in human blood are affected by gender but not by age or natural hormone cycles.

Previously, we reported on inter-individual and gender specific variations of LINE-1 methylation in healthy individuals. In this study, we investigated whether this variability could be influenced by age or sex hormones in humans. To this end, we studied LINE-1 methylation in vivo in blood-derived D...

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Bibliographic Details
Main Authors: Osman El-Maarri, Maja Walier, Frank Behne, Jan van Üüm, Heike Singer, Amalia Diaz-Lacava, Nicole Nüsgen, Barbara Niemann, Matthias Watzka, Jochen Reinsberg, Hans van der Ven, Thomas Wienker, Birgit Stoffel-Wagner, Rainer Schwaab, Johannes Oldenburg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3023801?pdf=render

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