Adherence to antiretroviral therapy among HIV infected pregnant women in public health sectors: a pilot of Chilenje level one Hospital Lusaka, Zambia
INTRODUCTION: regular use of Antiretroviral Therapy (ART) in pregnancy and breastfeeding reduces the odds of Mother-to-Child HIV Transmission (MTCT). However, adherence to ART is critical for MTCT to be successful. The present study investigated factors that influence adherence to ART among HIV infe...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
The Pan African Medical Journal
2020-02-01
|
| Series: | The Pan African Medical Journal |
| Subjects: | |
| Online Access: |
https://www.panafrican-med-journal.com/content/article/35/49/pdf/49.pdf
|
| _version_ | 1818909671805681664 |
|---|---|
| author | Moses Mukosha Grace Chiyesu Bellington Vwalika |
| author_facet | Moses Mukosha Grace Chiyesu Bellington Vwalika |
| author_sort | Moses Mukosha |
| collection | DOAJ |
| description | INTRODUCTION: regular use of Antiretroviral Therapy (ART) in pregnancy and breastfeeding reduces the odds of Mother-to-Child HIV Transmission (MTCT). However, adherence to ART is critical for MTCT to be successful. The present study investigated factors that influence adherence to ART among HIV infected pregnant women in Zambia. METHODS: the cross-sectional study design was conducted involving 71 HIV infected pregnant women who were advised to join the Prevention of Mother-to-Child HIV Transmission (PMTCT) program during their routine Antenatal clinic (ANC) visit and were on ART for more than six months. We used the Medication Possession Ratio (MPR) to quantify adherence levels. We used logistic regression to establish factors that influence adherence to ART. RESULTS: a total of 71 HIV infected pregnant women with a median age of 27years (IQR, 25-30) were enrolled in the study. There was evidence of a difference in adherence levels between pregnant women above 30 years and ones between 15 years and 30 years (P=0.001). Median adherence levels in this group were found to be at 96%(IQR 89-97). The main predictor of adherence in this population was marital status (being on separation) and age. The women who were on separation were 0.14 times less likely to adhere to option B+ compared to married women. CONCLUSION: adherence to option B+ among pregnant women is low. Adherence was significantly influenced by marital status (being on separation) and age. Efforts to improve adherence should be directed towards women on separation and young adults ( 30 years of age). |
| first_indexed | 2024-12-19T22:30:37Z |
| format | Article |
| id | doaj.art-176e2cf0dd1f448a95e585be6a500dca |
| institution | Directory Open Access Journal |
| issn | 1937-8688 1937-8688 |
| language | English |
| last_indexed | 2024-12-19T22:30:37Z |
| publishDate | 2020-02-01 |
| publisher | The Pan African Medical Journal |
| record_format | Article |
| series | The Pan African Medical Journal |
| spelling | doaj.art-176e2cf0dd1f448a95e585be6a500dca2022-12-21T20:03:21ZengThe Pan African Medical JournalThe Pan African Medical Journal1937-86881937-86882020-02-01354910.11604/pamj.2020.35.49.2007820078Adherence to antiretroviral therapy among HIV infected pregnant women in public health sectors: a pilot of Chilenje level one Hospital Lusaka, ZambiaMoses Mukosha0Grace Chiyesu1Bellington Vwalika2 Department of Pharmacy, University of Zambia, Lusaka, Zambia Faculty of Pharmacy Nutrition and Dietetics, Apex Medical University, Lusaka, Zambia Department of Obstetrics and Gynecology, University of Zambia, Lusaka, Zambia INTRODUCTION: regular use of Antiretroviral Therapy (ART) in pregnancy and breastfeeding reduces the odds of Mother-to-Child HIV Transmission (MTCT). However, adherence to ART is critical for MTCT to be successful. The present study investigated factors that influence adherence to ART among HIV infected pregnant women in Zambia. METHODS: the cross-sectional study design was conducted involving 71 HIV infected pregnant women who were advised to join the Prevention of Mother-to-Child HIV Transmission (PMTCT) program during their routine Antenatal clinic (ANC) visit and were on ART for more than six months. We used the Medication Possession Ratio (MPR) to quantify adherence levels. We used logistic regression to establish factors that influence adherence to ART. RESULTS: a total of 71 HIV infected pregnant women with a median age of 27years (IQR, 25-30) were enrolled in the study. There was evidence of a difference in adherence levels between pregnant women above 30 years and ones between 15 years and 30 years (P=0.001). Median adherence levels in this group were found to be at 96%(IQR 89-97). The main predictor of adherence in this population was marital status (being on separation) and age. The women who were on separation were 0.14 times less likely to adhere to option B+ compared to married women. CONCLUSION: adherence to option B+ among pregnant women is low. Adherence was significantly influenced by marital status (being on separation) and age. Efforts to improve adherence should be directed towards women on separation and young adults ( 30 years of age). https://www.panafrican-med-journal.com/content/article/35/49/pdf/49.pdf hivadherencezambiaantiretroviral therapy (option b+) |
| spellingShingle | Moses Mukosha Grace Chiyesu Bellington Vwalika Adherence to antiretroviral therapy among HIV infected pregnant women in public health sectors: a pilot of Chilenje level one Hospital Lusaka, Zambia The Pan African Medical Journal hiv adherence zambia antiretroviral therapy (option b+) |
| title | Adherence to antiretroviral therapy among HIV infected pregnant women in public health sectors: a pilot of Chilenje level one Hospital Lusaka, Zambia |
| title_full | Adherence to antiretroviral therapy among HIV infected pregnant women in public health sectors: a pilot of Chilenje level one Hospital Lusaka, Zambia |
| title_fullStr | Adherence to antiretroviral therapy among HIV infected pregnant women in public health sectors: a pilot of Chilenje level one Hospital Lusaka, Zambia |
| title_full_unstemmed | Adherence to antiretroviral therapy among HIV infected pregnant women in public health sectors: a pilot of Chilenje level one Hospital Lusaka, Zambia |
| title_short | Adherence to antiretroviral therapy among HIV infected pregnant women in public health sectors: a pilot of Chilenje level one Hospital Lusaka, Zambia |
| title_sort | adherence to antiretroviral therapy among hiv infected pregnant women in public health sectors a pilot of chilenje level one hospital lusaka zambia |
| topic | hiv adherence zambia antiretroviral therapy (option b+) |
| url |
https://www.panafrican-med-journal.com/content/article/35/49/pdf/49.pdf
|
| work_keys_str_mv | AT mosesmukosha adherencetoantiretroviraltherapyamonghivinfectedpregnantwomeninpublichealthsectorsapilotofchilenjelevelonehospitallusakazambia AT gracechiyesu adherencetoantiretroviraltherapyamonghivinfectedpregnantwomeninpublichealthsectorsapilotofchilenjelevelonehospitallusakazambia AT bellingtonvwalika adherencetoantiretroviraltherapyamonghivinfectedpregnantwomeninpublichealthsectorsapilotofchilenjelevelonehospitallusakazambia |