Ex vivo intervertebral disc cultures: degeneration-induction methods and their implications for clinical translation

Ex vivo intervertebral disc cultures: degeneration-induction methods and their implications for clinical translation

Because low back pain is frequently a result of intervertebral disc degeneration (IVDD), strategies to regenerate or repair the IVD are currently being investigated. Often, ex vivo disc cultures of non-human IVD organs or tissue explants are used that usually do not exhibit natural IVDD. Therefore,...

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Bibliographic Details
Main Authors: E Salzer, TC Schmitz, VHM Mouser, A Vernengo, B Gantenbein, JU Jansen, C Neidlinger-Wilke, H-J Wilke, S Grad, CL Le Maitre, MA Tryfonidou, K Ito
Format: Article
Language:English
Published: AO Research Institute Davos 2023-03-01
Series:European Cells & Materials
Subjects:
disc culture
organ culture
explant culture
3r
low back pain
Online Access:https://www.ecmjournal.org/papers/vol045/pdf/v045a07.pdf

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https://www.ecmjournal.org/papers/vol045/pdf/v045a07.pdf

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