Genetic Ablation of the ClC-2 Cl- Channel Disrupts Mouse Gastric Parietal Cell Acid Secretion.

Genetic Ablation of the ClC-2 Cl- Channel Disrupts Mouse Gastric Parietal Cell Acid Secretion.

The present studies were designed to examine the effects of ClC-2 ablation on cellular morphology, parietal cell abundance, H/K ATPase expression, parietal cell ultrastructure and acid secretion using WT and ClC-2-/- mouse stomachs. Cellular histology, morphology and proteins were examined using ima...

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Bibliographic Details
Main Authors: Meghali P Nighot, Prashant K Nighot, Thomas Y Ma, Danuta H Malinowska, Gary E Shull, John Cuppoletti, Anthony T Blikslager
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4574764?pdf=render

Internet

http://europepmc.org/articles/PMC4574764?pdf=render

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