Pollutant Degrading Enzyme: Catalytic Mechanisms and Their Expanded Applications
The treatment of environmental pollution by microorganisms and their enzymes is an innovative and socially acceptable alternative to traditional remediation approaches. Microbial biodegradation is often characterized with high efficiency as this process is catalyzed via degrading enzymes. Various na...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-08-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/26/16/4751 |
| _version_ | 1797522757795184640 |
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| author | Anming Xu Xiaoxiao Zhang Shilei Wu Ning Xu Yan Huang Xin Yan Jie Zhou Zhongli Cui Weiliang Dong |
| author_facet | Anming Xu Xiaoxiao Zhang Shilei Wu Ning Xu Yan Huang Xin Yan Jie Zhou Zhongli Cui Weiliang Dong |
| author_sort | Anming Xu |
| collection | DOAJ |
| description | The treatment of environmental pollution by microorganisms and their enzymes is an innovative and socially acceptable alternative to traditional remediation approaches. Microbial biodegradation is often characterized with high efficiency as this process is catalyzed via degrading enzymes. Various naturally isolated microorganisms were demonstrated to have considerable ability to mitigate many environmental pollutants without external intervention. However, only a small fraction of these strains are studied in detail to reveal the mechanisms at the enzyme level, which strictly limited the enhancement of the degradation efficiency. Accordingly, this review will comprehensively summarize the function of various degrading enzymes with an emphasis on catalytic mechanisms. We also inspect the expanded applications of these pollutant-degrading enzymes in industrial processes. An in-depth understanding of the catalytic mechanism of enzymes will be beneficial for exploring and exploiting more degrading enzyme resources and thus ameliorate concerns associated with the ineffective biodegradation of recalcitrant and xenobiotic contaminants with the help of gene-editing technology and synthetic biology. |
| first_indexed | 2024-03-10T08:32:53Z |
| format | Article |
| id | doaj.art-177417bf5a994ae1a9f59242a4afeee0 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T08:32:53Z |
| publishDate | 2021-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-177417bf5a994ae1a9f59242a4afeee02023-11-22T08:51:26ZengMDPI AGMolecules1420-30492021-08-012616475110.3390/molecules26164751Pollutant Degrading Enzyme: Catalytic Mechanisms and Their Expanded ApplicationsAnming Xu0Xiaoxiao Zhang1Shilei Wu2Ning Xu3Yan Huang4Xin Yan5Jie Zhou6Zhongli Cui7Weiliang Dong8State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211800, ChinaState Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211800, ChinaState Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211800, ChinaState Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211800, ChinaKey Laboratory of Agricultural Environmental Microbiology, Ministry of Agriculture and Rural Affairs, College of Life Sciences, Nanjing Agricultural University, Nanjing 210095, ChinaKey Laboratory of Agricultural Environmental Microbiology, Ministry of Agriculture and Rural Affairs, College of Life Sciences, Nanjing Agricultural University, Nanjing 210095, ChinaState Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211800, ChinaKey Laboratory of Agricultural Environmental Microbiology, Ministry of Agriculture and Rural Affairs, College of Life Sciences, Nanjing Agricultural University, Nanjing 210095, ChinaState Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211800, ChinaThe treatment of environmental pollution by microorganisms and their enzymes is an innovative and socially acceptable alternative to traditional remediation approaches. Microbial biodegradation is often characterized with high efficiency as this process is catalyzed via degrading enzymes. Various naturally isolated microorganisms were demonstrated to have considerable ability to mitigate many environmental pollutants without external intervention. However, only a small fraction of these strains are studied in detail to reveal the mechanisms at the enzyme level, which strictly limited the enhancement of the degradation efficiency. Accordingly, this review will comprehensively summarize the function of various degrading enzymes with an emphasis on catalytic mechanisms. We also inspect the expanded applications of these pollutant-degrading enzymes in industrial processes. An in-depth understanding of the catalytic mechanism of enzymes will be beneficial for exploring and exploiting more degrading enzyme resources and thus ameliorate concerns associated with the ineffective biodegradation of recalcitrant and xenobiotic contaminants with the help of gene-editing technology and synthetic biology.https://www.mdpi.com/1420-3049/26/16/4751microbial enzymecatalytic mechanismbiodegradationapplicationenvironmental pollutants |
| spellingShingle | Anming Xu Xiaoxiao Zhang Shilei Wu Ning Xu Yan Huang Xin Yan Jie Zhou Zhongli Cui Weiliang Dong Pollutant Degrading Enzyme: Catalytic Mechanisms and Their Expanded Applications Molecules microbial enzyme catalytic mechanism biodegradation application environmental pollutants |
| title | Pollutant Degrading Enzyme: Catalytic Mechanisms and Their Expanded Applications |
| title_full | Pollutant Degrading Enzyme: Catalytic Mechanisms and Their Expanded Applications |
| title_fullStr | Pollutant Degrading Enzyme: Catalytic Mechanisms and Their Expanded Applications |
| title_full_unstemmed | Pollutant Degrading Enzyme: Catalytic Mechanisms and Their Expanded Applications |
| title_short | Pollutant Degrading Enzyme: Catalytic Mechanisms and Their Expanded Applications |
| title_sort | pollutant degrading enzyme catalytic mechanisms and their expanded applications |
| topic | microbial enzyme catalytic mechanism biodegradation application environmental pollutants |
| url | https://www.mdpi.com/1420-3049/26/16/4751 |
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