N-acetyl cysteine mitigates the acute effects of cocaine-induced toxicity in astroglia-like cells.

N-acetyl cysteine mitigates the acute effects of cocaine-induced toxicity in astroglia-like cells.

Cocaine has a short half-life of only about an hour but its effects, predominantly on the central nervous system (CNS), are fairly long-lasting. Of all cells within the CNS, astrocytes may be the first to display cocaine toxicity owing to their relative abundance in the brain. Cocaine entry could tr...

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Bibliographic Details
Main Authors: Ramesh B Badisa, Sanjay S Kumar, Elizabeth Mazzio, Rasheda D Haughbrook, John R Allen, Michael W Davidson, Cheryl A Fitch-Pye, Carl B Goodman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4305286?pdf=render

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