Association Between Cognitive Function and Early Life Experiences in Patients with Alcohol Use Disorder
IntroductionEarly life experiences could be potential risk factors for the development of alcohol use disorder. In similar circumstances, it might also influence cognitive impairment in later life. However, the relationship between early life experience and cognitive function in people with alcohol...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-08-01
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| Series: | Frontiers in Psychiatry |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fpsyt.2020.00792/full |
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| author | Fangshuo Cheng Fangshuo Cheng Shu Cui Shu Cui Chao Zhang Ling Zhang Ling Zhang Lei Wang Lei Wang Qiuyu Yuan Qiuyu Yuan Cui Huang Cui Huang Kai Zhang Kai Zhang Xiaoqin Zhou Xiaoqin Zhou |
| author_facet | Fangshuo Cheng Fangshuo Cheng Shu Cui Shu Cui Chao Zhang Ling Zhang Ling Zhang Lei Wang Lei Wang Qiuyu Yuan Qiuyu Yuan Cui Huang Cui Huang Kai Zhang Kai Zhang Xiaoqin Zhou Xiaoqin Zhou |
| author_sort | Fangshuo Cheng |
| collection | DOAJ |
| description | IntroductionEarly life experiences could be potential risk factors for the development of alcohol use disorder. In similar circumstances, it might also influence cognitive impairment in later life. However, the relationship between early life experience and cognitive function in people with alcohol use disorders is unclear. The current study examined the effects of early social environments and experiences on cognitive function in patients with alcohol use disorder.MethodsA total of 37 adult male patients with alcohol use disorder and 30 healthy control (HC) subjects were enrolled. The MATRICS Cognitive Consensus Battery (MCCB) was used to evaluate cognitive function. The Childhood Trauma Questionnaire (CTQ) and the Revised Adult Attachment Scale (RAAS) were used to evaluate early life experiences of the participants. The RAAS was used to evaluate the attachment patterns of participants.ResultsCompared with the HC group, the alcohol use disorder group reported higher levels of childhood abuse and were more likely to form an insecure attachment style. Patients with alcohol use disorder who experienced trauma performed worse in terms of discrete cognitive parameters such as social cognition, reasoning and problem solving compared to patients without trauma. Importantly, emotional neglect and social comfort were significantly associated with individual social cognitive skills.ConclusionsOur results suggest that the cognitive function of patients with alcohol use disorder, especially social cognitive function, is affected by early life experiences. |
| first_indexed | 2024-04-12T08:38:11Z |
| format | Article |
| id | doaj.art-1780acedee6342cdb266e44502a1807b |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-04-12T08:38:11Z |
| publishDate | 2020-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-1780acedee6342cdb266e44502a1807b2022-12-22T03:39:57ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402020-08-011110.3389/fpsyt.2020.00792578908Association Between Cognitive Function and Early Life Experiences in Patients with Alcohol Use DisorderFangshuo Cheng0Fangshuo Cheng1Shu Cui2Shu Cui3Chao Zhang4Ling Zhang5Ling Zhang6Lei Wang7Lei Wang8Qiuyu Yuan9Qiuyu Yuan10Cui Huang11Cui Huang12Kai Zhang13Kai Zhang14Xiaoqin Zhou15Xiaoqin Zhou16Department of Psychiatry, Chaohu Hospital, Anhui Medical University, Hefei, ChinaAnhui Psychiatric Center, Anhui Medical University, Hefei, ChinaDepartment of Psychiatry, Chaohu Hospital, Anhui Medical University, Hefei, ChinaAnhui Psychiatric Center, Anhui Medical University, Hefei, ChinaDepartment of Pediatrics, Fuyang People's Hospital, Fuyang, ChinaDepartment of Psychiatry, Chaohu Hospital, Anhui Medical University, Hefei, ChinaAnhui Psychiatric Center, Anhui Medical University, Hefei, ChinaDepartment of Psychiatry, Chaohu Hospital, Anhui Medical University, Hefei, ChinaAnhui Psychiatric Center, Anhui Medical University, Hefei, ChinaDepartment of Psychiatry, Chaohu Hospital, Anhui Medical University, Hefei, ChinaAnhui Psychiatric Center, Anhui Medical University, Hefei, ChinaDepartment of Psychiatry, Chaohu Hospital, Anhui Medical University, Hefei, ChinaAnhui Psychiatric Center, Anhui Medical University, Hefei, ChinaDepartment of Psychiatry, Chaohu Hospital, Anhui Medical University, Hefei, ChinaAnhui Psychiatric Center, Anhui Medical University, Hefei, ChinaDepartment of Psychiatry, Chaohu Hospital, Anhui Medical University, Hefei, ChinaAnhui Psychiatric Center, Anhui Medical University, Hefei, ChinaIntroductionEarly life experiences could be potential risk factors for the development of alcohol use disorder. In similar circumstances, it might also influence cognitive impairment in later life. However, the relationship between early life experience and cognitive function in people with alcohol use disorders is unclear. The current study examined the effects of early social environments and experiences on cognitive function in patients with alcohol use disorder.MethodsA total of 37 adult male patients with alcohol use disorder and 30 healthy control (HC) subjects were enrolled. The MATRICS Cognitive Consensus Battery (MCCB) was used to evaluate cognitive function. The Childhood Trauma Questionnaire (CTQ) and the Revised Adult Attachment Scale (RAAS) were used to evaluate early life experiences of the participants. The RAAS was used to evaluate the attachment patterns of participants.ResultsCompared with the HC group, the alcohol use disorder group reported higher levels of childhood abuse and were more likely to form an insecure attachment style. Patients with alcohol use disorder who experienced trauma performed worse in terms of discrete cognitive parameters such as social cognition, reasoning and problem solving compared to patients without trauma. Importantly, emotional neglect and social comfort were significantly associated with individual social cognitive skills.ConclusionsOur results suggest that the cognitive function of patients with alcohol use disorder, especially social cognitive function, is affected by early life experiences.https://www.frontiersin.org/article/10.3389/fpsyt.2020.00792/fullearly life experiencesattachmentcognitive functionalcohol use disordersocial cognitive function |
| spellingShingle | Fangshuo Cheng Fangshuo Cheng Shu Cui Shu Cui Chao Zhang Ling Zhang Ling Zhang Lei Wang Lei Wang Qiuyu Yuan Qiuyu Yuan Cui Huang Cui Huang Kai Zhang Kai Zhang Xiaoqin Zhou Xiaoqin Zhou Association Between Cognitive Function and Early Life Experiences in Patients with Alcohol Use Disorder Frontiers in Psychiatry early life experiences attachment cognitive function alcohol use disorder social cognitive function |
| title | Association Between Cognitive Function and Early Life Experiences in Patients with Alcohol Use Disorder |
| title_full | Association Between Cognitive Function and Early Life Experiences in Patients with Alcohol Use Disorder |
| title_fullStr | Association Between Cognitive Function and Early Life Experiences in Patients with Alcohol Use Disorder |
| title_full_unstemmed | Association Between Cognitive Function and Early Life Experiences in Patients with Alcohol Use Disorder |
| title_short | Association Between Cognitive Function and Early Life Experiences in Patients with Alcohol Use Disorder |
| title_sort | association between cognitive function and early life experiences in patients with alcohol use disorder |
| topic | early life experiences attachment cognitive function alcohol use disorder social cognitive function |
| url | https://www.frontiersin.org/article/10.3389/fpsyt.2020.00792/full |
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