Effect of Medium Chain Triglycerides and Conjugated Linoleates Combined With Edible Oil on Fat Hoarding and Cognitive Function of Rat
The effects of constituted edible oils prepared from medium chain triglycerides and conjugated linoleates on fat accumulation and cognitive function of rats were investigated. Sixty SD rats were randomly divided into control (distilled water), lard, healthy oil and combined oil groups. The rats were...
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| Format: | Article |
| Language: | English |
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Academy of National Food and Strategic Reserves Administration
2022-07-01
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| Series: | Liang you shipin ke-ji |
| Subjects: | |
| Online Access: | http://lyspkj.ijournal.cn/lyspkj/article/abstract/20220420?st=article_issue |
| _version_ | 1827989104544972800 |
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| author | XU Yi-fei HONG Ming ZHOU Na YIN Xi-quan CAO Hong-ying |
| author_facet | XU Yi-fei HONG Ming ZHOU Na YIN Xi-quan CAO Hong-ying |
| author_sort | XU Yi-fei |
| collection | DOAJ |
| description | The effects of constituted edible oils prepared from medium chain triglycerides and conjugated linoleates on fat accumulation and cognitive function of rats were investigated. Sixty SD rats were randomly divided into control (distilled water), lard, healthy oil and combined oil groups. The rats were oral administration for 4 weeks. The body weight, food intake and water consumption of rats were recorded, while the cognitive function was investigated using morris water maze. The Lee’s index, as well as the weights of perirenal, abdominal, epididymal and epicardial fat were measured, besides, the blood was obtained for blood glucose, liver function, lipid metabolism, leptin and TNF-α testing. The structure of small intestine and liver lobules was observed. Compared with the control group, the weight of perirenal, epididymal and epicardial fat, as well as TNF-α and ALT were significantly higher in the lard group. Compared with the lard group, the fasting glucose values, ALT, the weight of perirenal, epididymis and epicardial fat, as well as TNF-α were significantly lower in the healthy oil group and combined oil group. Compared with the control and lard groups, the level of triglycerides was significantly lower in the combined low group. The reconstituted oil has potential benefits on controlling the increase of triglyceride level and inflammatory response induced by high amount of oil intake. |
| first_indexed | 2024-04-10T00:14:04Z |
| format | Article |
| id | doaj.art-17827711304e40b2ab9894d12cb21477 |
| institution | Directory Open Access Journal |
| issn | 1007-7561 |
| language | English |
| last_indexed | 2024-04-10T00:14:04Z |
| publishDate | 2022-07-01 |
| publisher | Academy of National Food and Strategic Reserves Administration |
| record_format | Article |
| series | Liang you shipin ke-ji |
| spelling | doaj.art-17827711304e40b2ab9894d12cb214772023-03-16T06:15:19ZengAcademy of National Food and Strategic Reserves AdministrationLiang you shipin ke-ji1007-75612022-07-0130412813510.16210/j.cnki.1007-7561.2022.04.017Effect of Medium Chain Triglycerides and Conjugated Linoleates Combined With Edible Oil on Fat Hoarding and Cognitive Function of RatXU Yi-fei0HONG Ming1ZHOU Na2YIN Xi-quan3CAO Hong-ying4 Shenzhen Traditional Chinese Medicine Hospital, the Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, Guangdong 518033, ChinaSchool of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, ChinaSchool of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, ChinaMaihe (Guangzhou) Industry Co., Ltd., Guangzhou, Guangdong 510555, ChinaSchool of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, ChinaThe effects of constituted edible oils prepared from medium chain triglycerides and conjugated linoleates on fat accumulation and cognitive function of rats were investigated. Sixty SD rats were randomly divided into control (distilled water), lard, healthy oil and combined oil groups. The rats were oral administration for 4 weeks. The body weight, food intake and water consumption of rats were recorded, while the cognitive function was investigated using morris water maze. The Lee’s index, as well as the weights of perirenal, abdominal, epididymal and epicardial fat were measured, besides, the blood was obtained for blood glucose, liver function, lipid metabolism, leptin and TNF-α testing. The structure of small intestine and liver lobules was observed. Compared with the control group, the weight of perirenal, epididymal and epicardial fat, as well as TNF-α and ALT were significantly higher in the lard group. Compared with the lard group, the fasting glucose values, ALT, the weight of perirenal, epididymis and epicardial fat, as well as TNF-α were significantly lower in the healthy oil group and combined oil group. Compared with the control and lard groups, the level of triglycerides was significantly lower in the combined low group. The reconstituted oil has potential benefits on controlling the increase of triglyceride level and inflammatory response induced by high amount of oil intake.http://lyspkj.ijournal.cn/lyspkj/article/abstract/20220420?st=article_issuemedium chain triglyceridesconjugated linoleatesfat accumulationcognitive function |
| spellingShingle | XU Yi-fei HONG Ming ZHOU Na YIN Xi-quan CAO Hong-ying Effect of Medium Chain Triglycerides and Conjugated Linoleates Combined With Edible Oil on Fat Hoarding and Cognitive Function of Rat Liang you shipin ke-ji medium chain triglycerides conjugated linoleates fat accumulation cognitive function |
| title | Effect of Medium Chain Triglycerides and Conjugated Linoleates Combined With Edible Oil on Fat Hoarding and Cognitive Function of Rat |
| title_full | Effect of Medium Chain Triglycerides and Conjugated Linoleates Combined With Edible Oil on Fat Hoarding and Cognitive Function of Rat |
| title_fullStr | Effect of Medium Chain Triglycerides and Conjugated Linoleates Combined With Edible Oil on Fat Hoarding and Cognitive Function of Rat |
| title_full_unstemmed | Effect of Medium Chain Triglycerides and Conjugated Linoleates Combined With Edible Oil on Fat Hoarding and Cognitive Function of Rat |
| title_short | Effect of Medium Chain Triglycerides and Conjugated Linoleates Combined With Edible Oil on Fat Hoarding and Cognitive Function of Rat |
| title_sort | effect of medium chain triglycerides and conjugated linoleates combined with edible oil on fat hoarding and cognitive function of rat |
| topic | medium chain triglycerides conjugated linoleates fat accumulation cognitive function |
| url | http://lyspkj.ijournal.cn/lyspkj/article/abstract/20220420?st=article_issue |
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