Adaptation of Oxidative Phosphorylation Machinery Compensates for Hepatic Lipotoxicity in Early Stages of MAFLD

Adaptation of Oxidative Phosphorylation Machinery Compensates for Hepatic Lipotoxicity in Early Stages of MAFLD

Alterations in mitochondrial function are an important control variable in the progression of metabolic dysfunction-associated fatty liver disease (MAFLD), while also noted by increased de novo lipogenesis (DNL) and hepatic insulin resistance. We hypothesized that the organization and function of a...

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Bibliographic Details
Main Authors: Pia Fahlbusch, Aleksandra Nikolic, Sonja Hartwig, Sylvia Jacob, Ulrike Kettel, Cornelia Köllmer, Hadi Al-Hasani, Stefan Lehr, Dirk Müller-Wieland, Birgit Knebel, Jörg Kotzka
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
fatty liver
hepatic metabolism
mitochondria
substrate
subunit
Online Access:https://www.mdpi.com/1422-0067/23/12/6873

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https://www.mdpi.com/1422-0067/23/12/6873

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