Fetal lung maturity assessment with lamellar body count in women with obesity and excessive gestational weight gain
The aim of this study was to evaluate fetal lung maturation in term pregnant women with obesity and excessive gestational weight gain using the lamellar body count (LBC) test in amniotic fluid samples obtained during cesarean section. This retrospective study included women experiencing term pregnan...
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| Format: | Article |
| Language: | English |
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Society of Turaz Bilim
2023-12-01
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| Series: | Medicine Science |
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| Online Access: | https://www.medicinescience.org/?mno=166699 |
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| author | Aydin Ocal Sinem Tekin Filiz Yarsilikal Guleroglu Omer Gokhan Eyisoy Pelin Kulan Emine Yilmaz Guler Ali Cetin |
| author_facet | Aydin Ocal Sinem Tekin Filiz Yarsilikal Guleroglu Omer Gokhan Eyisoy Pelin Kulan Emine Yilmaz Guler Ali Cetin |
| author_sort | Aydin Ocal |
| collection | DOAJ |
| description | The aim of this study was to evaluate fetal lung maturation in term pregnant women with obesity and excessive gestational weight gain using the lamellar body count (LBC) test in amniotic fluid samples obtained during cesarean section. This retrospective study included women experiencing term pregnancies and undergoing cesarean delivery, categorized as normal weight (n=37), overweight (n=59), or obese (n=48) due to body mass index values of 18.5 to 24.9; 25 to 29.9; and ≥30, respectively, as well as presence of excessive weight gain during pregnancy. During cesarean delivery, amniotic fluid samples were obtained without contamination of blood or meconium. Lamellar bodies in these samples were quantified using a standard hematologic counter. No significant difference was found among the LBC of the normal weight, overweight, and obese groups [42 (32-60), 40 (26-63), and 43 (24-52) x103/µL; p=0.307], although there was a subtle decrease in the LBC of the obese group with excessive weight gain. Although it is noteworthy that the LBC in the amniotic fluid of mothers with obesity and excessive weight gain during pregnancy showed a partial decrease, this decrease did not reach statistical significance, likely due to the relatively low number of cases in the study groups. Additional research is warranted to elucidate the relationship between LBC alterations and the severity of obesity and weight gain during pregnancy. [Med-Science 2023; 12(4.000): 1278-83] |
| first_indexed | 2024-03-08T03:20:19Z |
| format | Article |
| id | doaj.art-1786020872f6432aa536b092c4558ee2 |
| institution | Directory Open Access Journal |
| issn | 2147-0634 |
| language | English |
| last_indexed | 2024-03-08T03:20:19Z |
| publishDate | 2023-12-01 |
| publisher | Society of Turaz Bilim |
| record_format | Article |
| series | Medicine Science |
| spelling | doaj.art-1786020872f6432aa536b092c4558ee22024-02-12T10:32:08ZengSociety of Turaz BilimMedicine Science2147-06342023-12-0112412788310.5455/medscience.2023.08.169166699Fetal lung maturity assessment with lamellar body count in women with obesity and excessive gestational weight gainAydin Ocal0Sinem Tekin1Filiz Yarsilikal Guleroglu2Omer Gokhan Eyisoy3Pelin Kulan4Emine Yilmaz Guler5Ali Cetin6Division of Perinatology, Department of Obstetrics and Gynecology, Haseki Training and Research Hospital, University of Health Science, Istanbul, Turkey Division of Perinatology, Department of Obstetrics and Gynecology, Haseki Training and Research Hospital, University of Health Science, Istanbul, Turkey Division of Perinatology, Department of Obstetrics and Gynecology, Haseki Training and Research Hospital, University of Health Science, Istanbul, Turkey Division of Perinatology, Department of Obstetrics and Gynecology, Zeynep Kamil Women's and Children's Training and Research Hospital, University of Health Science, Istanbul, Turkey Department of Biochemistry, Haseki Training and Research Hospital, University of Health Science, Istanbul, Turkey Department of Anesthesiology and Reanimation, Haseki Training and Research Hospital, University of Health Science, Istanbul, Turkey Division of Perinatology, Department of Obstetrics and Gynecology, Haseki Training and Research Hospital, University of Health Science, Istanbul, TurkeyThe aim of this study was to evaluate fetal lung maturation in term pregnant women with obesity and excessive gestational weight gain using the lamellar body count (LBC) test in amniotic fluid samples obtained during cesarean section. This retrospective study included women experiencing term pregnancies and undergoing cesarean delivery, categorized as normal weight (n=37), overweight (n=59), or obese (n=48) due to body mass index values of 18.5 to 24.9; 25 to 29.9; and ≥30, respectively, as well as presence of excessive weight gain during pregnancy. During cesarean delivery, amniotic fluid samples were obtained without contamination of blood or meconium. Lamellar bodies in these samples were quantified using a standard hematologic counter. No significant difference was found among the LBC of the normal weight, overweight, and obese groups [42 (32-60), 40 (26-63), and 43 (24-52) x103/µL; p=0.307], although there was a subtle decrease in the LBC of the obese group with excessive weight gain. Although it is noteworthy that the LBC in the amniotic fluid of mothers with obesity and excessive weight gain during pregnancy showed a partial decrease, this decrease did not reach statistical significance, likely due to the relatively low number of cases in the study groups. Additional research is warranted to elucidate the relationship between LBC alterations and the severity of obesity and weight gain during pregnancy. [Med-Science 2023; 12(4.000): 1278-83]https://www.medicinescience.org/?mno=166699fetal lung maturitygestational weight gainlamellar body countobesitypregnancy |
| spellingShingle | Aydin Ocal Sinem Tekin Filiz Yarsilikal Guleroglu Omer Gokhan Eyisoy Pelin Kulan Emine Yilmaz Guler Ali Cetin Fetal lung maturity assessment with lamellar body count in women with obesity and excessive gestational weight gain Medicine Science fetal lung maturity gestational weight gain lamellar body count obesity pregnancy |
| title | Fetal lung maturity assessment with lamellar body count in women with obesity and excessive gestational weight gain |
| title_full | Fetal lung maturity assessment with lamellar body count in women with obesity and excessive gestational weight gain |
| title_fullStr | Fetal lung maturity assessment with lamellar body count in women with obesity and excessive gestational weight gain |
| title_full_unstemmed | Fetal lung maturity assessment with lamellar body count in women with obesity and excessive gestational weight gain |
| title_short | Fetal lung maturity assessment with lamellar body count in women with obesity and excessive gestational weight gain |
| title_sort | fetal lung maturity assessment with lamellar body count in women with obesity and excessive gestational weight gain |
| topic | fetal lung maturity gestational weight gain lamellar body count obesity pregnancy |
| url | https://www.medicinescience.org/?mno=166699 |
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