Mosaic origins of a complex chimeric mitochondrial gene in Silene vulgaris.
Chimeric genes are significant sources of evolutionary innovation that are normally created when portions of two or more protein coding regions fuse to form a new open reading frame. In plant mitochondria astonishingly high numbers of different novel chimeric genes have been reported, where they are...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2012-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3288002?pdf=render |
| _version_ | 1818953015203201024 |
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| author | Helena Storchova Karel Müller Steffen Lau Matthew S Olson |
| author_facet | Helena Storchova Karel Müller Steffen Lau Matthew S Olson |
| author_sort | Helena Storchova |
| collection | DOAJ |
| description | Chimeric genes are significant sources of evolutionary innovation that are normally created when portions of two or more protein coding regions fuse to form a new open reading frame. In plant mitochondria astonishingly high numbers of different novel chimeric genes have been reported, where they are generated through processes of rearrangement and recombination. Nonetheless, because most studies do not find or report nucleotide variation within the same chimeric gene, evolution after the origination of these chimeric genes remains unstudied. Here we identify two alleles of a complex chimera in Silene vulgaris that are divergent in nucleotide sequence, genomic position relative to other mitochondrial genes, and expression patterns. Structural patterns suggest a history partially influenced by gene conversion between the chimeric gene and functional copies of subunit 1 of the mitochondrial ATP synthase gene (atp1). We identified small repeat structures within the chimeras that are likely recombination sites allowing generation of the chimera. These results establish the potential for chimeric gene divergence in different plant mitochondrial lineages within the same species. This result contrasts with the absence of diversity within mitochondrial chimeras found in crop species. |
| first_indexed | 2024-12-20T09:59:33Z |
| format | Article |
| id | doaj.art-1786b079087f4f68b905c0f55a92890d |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-20T09:59:33Z |
| publishDate | 2012-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-1786b079087f4f68b905c0f55a92890d2022-12-21T19:44:22ZengPublic Library of Science (PLoS)PLoS ONE1932-62032012-01-0172e3040110.1371/journal.pone.0030401Mosaic origins of a complex chimeric mitochondrial gene in Silene vulgaris.Helena StorchovaKarel MüllerSteffen LauMatthew S OlsonChimeric genes are significant sources of evolutionary innovation that are normally created when portions of two or more protein coding regions fuse to form a new open reading frame. In plant mitochondria astonishingly high numbers of different novel chimeric genes have been reported, where they are generated through processes of rearrangement and recombination. Nonetheless, because most studies do not find or report nucleotide variation within the same chimeric gene, evolution after the origination of these chimeric genes remains unstudied. Here we identify two alleles of a complex chimera in Silene vulgaris that are divergent in nucleotide sequence, genomic position relative to other mitochondrial genes, and expression patterns. Structural patterns suggest a history partially influenced by gene conversion between the chimeric gene and functional copies of subunit 1 of the mitochondrial ATP synthase gene (atp1). We identified small repeat structures within the chimeras that are likely recombination sites allowing generation of the chimera. These results establish the potential for chimeric gene divergence in different plant mitochondrial lineages within the same species. This result contrasts with the absence of diversity within mitochondrial chimeras found in crop species.http://europepmc.org/articles/PMC3288002?pdf=render |
| spellingShingle | Helena Storchova Karel Müller Steffen Lau Matthew S Olson Mosaic origins of a complex chimeric mitochondrial gene in Silene vulgaris. PLoS ONE |
| title | Mosaic origins of a complex chimeric mitochondrial gene in Silene vulgaris. |
| title_full | Mosaic origins of a complex chimeric mitochondrial gene in Silene vulgaris. |
| title_fullStr | Mosaic origins of a complex chimeric mitochondrial gene in Silene vulgaris. |
| title_full_unstemmed | Mosaic origins of a complex chimeric mitochondrial gene in Silene vulgaris. |
| title_short | Mosaic origins of a complex chimeric mitochondrial gene in Silene vulgaris. |
| title_sort | mosaic origins of a complex chimeric mitochondrial gene in silene vulgaris |
| url | http://europepmc.org/articles/PMC3288002?pdf=render |
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