Measuring exposure to organochlorinated pesticides

Environmental epidemiological investigations in cancer remain, with rare exceptions, inconclusive. The difficulties of establishing patterns of measurements of exposure in the human body is one of the limitations of these studies. The findings of six recent epidemiological studies that analyzed the...

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Main Author: Gulnar Azevedo e Silva Mendonça
Format: Article
Language:English
Published: Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz
Series:Cadernos de Saúde Pública
Subjects:
Online Access:http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0102-311X1998000700018&lng=en&tlng=en
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author Gulnar Azevedo e Silva Mendonça
author_facet Gulnar Azevedo e Silva Mendonça
author_sort Gulnar Azevedo e Silva Mendonça
collection DOAJ
description Environmental epidemiological investigations in cancer remain, with rare exceptions, inconclusive. The difficulties of establishing patterns of measurements of exposure in the human body is one of the limitations of these studies. The findings of six recent epidemiological studies that analyzed the association between organochlorinated compounds and breast cancer are reviewed in considering the problems of measuring environmental exposure through biological markers. The epidemiological evidence based on these studies do not indicate a risk of breast cancer related to organochlorines. Some aspects that may partially explain this absence of risk are discussed regarding the investigation of environmental carcinogenic agents in populations with low but homogeneously sprayed levels of exposure.
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spelling doaj.art-178818b4dadd4d2aa0046cf9fa3f18752022-12-22T00:27:50ZengEscola Nacional de Saúde Pública, Fundação Oswaldo CruzCadernos de Saúde Pública0102-311X1678-446414suppl 3S177S179S0102-311X1998000700018Measuring exposure to organochlorinated pesticidesGulnar Azevedo e Silva Mendonça0Universidade do Estado do Rio de JaneiroEnvironmental epidemiological investigations in cancer remain, with rare exceptions, inconclusive. The difficulties of establishing patterns of measurements of exposure in the human body is one of the limitations of these studies. The findings of six recent epidemiological studies that analyzed the association between organochlorinated compounds and breast cancer are reviewed in considering the problems of measuring environmental exposure through biological markers. The epidemiological evidence based on these studies do not indicate a risk of breast cancer related to organochlorines. Some aspects that may partially explain this absence of risk are discussed regarding the investigation of environmental carcinogenic agents in populations with low but homogeneously sprayed levels of exposure.http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0102-311X1998000700018&lng=en&tlng=enbreast neoplasmspesticidesenvironmental exposure
spellingShingle Gulnar Azevedo e Silva Mendonça
Measuring exposure to organochlorinated pesticides
Cadernos de Saúde Pública
breast neoplasms
pesticides
environmental exposure
title Measuring exposure to organochlorinated pesticides
title_full Measuring exposure to organochlorinated pesticides
title_fullStr Measuring exposure to organochlorinated pesticides
title_full_unstemmed Measuring exposure to organochlorinated pesticides
title_short Measuring exposure to organochlorinated pesticides
title_sort measuring exposure to organochlorinated pesticides
topic breast neoplasms
pesticides
environmental exposure
url http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0102-311X1998000700018&lng=en&tlng=en
work_keys_str_mv AT gulnarazevedoesilvamendonca measuringexposuretoorganochlorinatedpesticides