mleS in Staphylococcus aureus Contributes to Microaerobic Metabolic Activity, Abscess Formation, and Survival in Macrophages

mleS in Staphylococcus aureus Contributes to Microaerobic Metabolic Activity, Abscess Formation, and Survival in Macrophages

ABSTRACT Staphylococcus aureus is subdivided into lineages termed sequence types (STs), infections of which necessitate the expression of virulence factors and metabolic adaptation to the host niche. Given that mechanisms underlying the dynamic replacement of sequence types in S. aureus populations...

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Bibliographic Details
Main Authors: Fengning Chen, Yuyao Yin, Hongbin Chen, Shuguang Li, Guankun Yin, Hui Wang
Format: Article
Language:English
Published: American Society for Microbiology 2023-06-01
Series:Microbiology Spectrum
Subjects:
NAD+-dependent malolactic enzyme coding gene (mleS)
Staphylococcus aureus
macrophage survival
metabolism
mouse skin abscess
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00909-23

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