Prognostic and predictive biomarkers for response to neoadjuvant chemoradiation in esophageal adenocarcinoma

Prognostic and predictive biomarkers for response to neoadjuvant chemoradiation in esophageal adenocarcinoma

Abstract Background Esophageal adenocarcinoma is a lethal disease. For locally advanced patients, neoadjuvant chemoradiotherapy followed by surgery is the standard of care. Risk stratification relies heavily on clinicopathologic features, particularly pathologic response, which is inadequate, theref...

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Bibliographic Details
Main Authors: Hirsch Matani, Divya Sahu, Michael Paskewicz, Anastasia Gorbunova, Ashten N. Omstead, Rodney Wegner, Gene G. Finley, Blair A. Jobe, Ronan J. Kelly, Ali H. Zaidi, Ajay Goel
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Biomarker Research
Subjects:
Esophageal adenocarcinoma
Risk stratification
CROSS regimen
EPHA5
BCL6
ERBB2
Online Access:https://doi.org/10.1186/s40364-022-00429-6

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