MMP-14 overexpression correlates with the neurodegenerative process in familial amyloidotic polyneuropathy
Levels of matrix metalloproteases (MMPs) can be differentially regulated in response to injury or neurological diseases. For instance, it is known that selective and short-term inhibition of MMP-14, a membrane-type 1 MMP, accelerates axon regeneration. Because axon growth and regeneration is impaire...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2017-10-01
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Series: | Disease Models & Mechanisms |
Subjects: | |
Online Access: | http://dmm.biologists.org/content/10/10/1253 |