Magnesium Alloys With Tunable Interfaces as Bone Implant Materials
Magnesium (Mg) based biodegradable materials are a new generation orthopedic implant materials that are intended to possess same mechanical properties as that of bone. Mg alloys are considered as promising substitutes to permanent implants due to their biodegradability in the physiological environme...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-06-01
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| Series: | Frontiers in Bioengineering and Biotechnology |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fbioe.2020.00564/full |
| _version_ | 1811222844872327168 |
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| author | Mostafizur Rahman Naba K. Dutta Namita Roy Choudhury |
| author_facet | Mostafizur Rahman Naba K. Dutta Namita Roy Choudhury |
| author_sort | Mostafizur Rahman |
| collection | DOAJ |
| description | Magnesium (Mg) based biodegradable materials are a new generation orthopedic implant materials that are intended to possess same mechanical properties as that of bone. Mg alloys are considered as promising substitutes to permanent implants due to their biodegradability in the physiological environment. However, rapid corrosion rate is one of the major constraints of using Mg alloys in clinical applications in spite of their excellent biocompatibility. Approaches to overcome the limitations include the selection of adequate alloying elements, proper surface treatment, surface modification with coating to control the degradation rate. This review focuses on current advances on surface engineering of Mg based biomaterials for biomedical applications. The review begins with a description of corrosion mechanism of Mg alloy, the requirement for appropriate surface functionalization/coatings, their structure-property-performance relationship, and suitability for biomedical applications. The control of physico-chemical properties such as wettability, surface morphology, surface chemistry, and surface functional groups of the coating tailored by various approaches forms the pivotal part of the review. Chemical surface treatment offers initial protection from corrosion and inorganic coating like hydroxyapatite (HA) improves the biocompatibility of the substrate. Considering the demand of ideal implant materials, multilayer hybrid coatings on Mg alloy in combination with chemical pretreatment or inorganic HA coating, and protein-based polymer coating could be a promising technique to improve corrosion resistance and promote biocompatibility of Mg-based alloys. |
| first_indexed | 2024-04-12T08:22:48Z |
| format | Article |
| id | doaj.art-17959e95e91f4b65a87f69000ef4ad26 |
| institution | Directory Open Access Journal |
| issn | 2296-4185 |
| language | English |
| last_indexed | 2024-04-12T08:22:48Z |
| publishDate | 2020-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj.art-17959e95e91f4b65a87f69000ef4ad262022-12-22T03:40:30ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852020-06-01810.3389/fbioe.2020.00564532648Magnesium Alloys With Tunable Interfaces as Bone Implant MaterialsMostafizur RahmanNaba K. DuttaNamita Roy ChoudhuryMagnesium (Mg) based biodegradable materials are a new generation orthopedic implant materials that are intended to possess same mechanical properties as that of bone. Mg alloys are considered as promising substitutes to permanent implants due to their biodegradability in the physiological environment. However, rapid corrosion rate is one of the major constraints of using Mg alloys in clinical applications in spite of their excellent biocompatibility. Approaches to overcome the limitations include the selection of adequate alloying elements, proper surface treatment, surface modification with coating to control the degradation rate. This review focuses on current advances on surface engineering of Mg based biomaterials for biomedical applications. The review begins with a description of corrosion mechanism of Mg alloy, the requirement for appropriate surface functionalization/coatings, their structure-property-performance relationship, and suitability for biomedical applications. The control of physico-chemical properties such as wettability, surface morphology, surface chemistry, and surface functional groups of the coating tailored by various approaches forms the pivotal part of the review. Chemical surface treatment offers initial protection from corrosion and inorganic coating like hydroxyapatite (HA) improves the biocompatibility of the substrate. Considering the demand of ideal implant materials, multilayer hybrid coatings on Mg alloy in combination with chemical pretreatment or inorganic HA coating, and protein-based polymer coating could be a promising technique to improve corrosion resistance and promote biocompatibility of Mg-based alloys.https://www.frontiersin.org/article/10.3389/fbioe.2020.00564/fullinterfacial engineeringmagnesium alloysurface coatingcorrosionbiomedical application |
| spellingShingle | Mostafizur Rahman Naba K. Dutta Namita Roy Choudhury Magnesium Alloys With Tunable Interfaces as Bone Implant Materials Frontiers in Bioengineering and Biotechnology interfacial engineering magnesium alloy surface coating corrosion biomedical application |
| title | Magnesium Alloys With Tunable Interfaces as Bone Implant Materials |
| title_full | Magnesium Alloys With Tunable Interfaces as Bone Implant Materials |
| title_fullStr | Magnesium Alloys With Tunable Interfaces as Bone Implant Materials |
| title_full_unstemmed | Magnesium Alloys With Tunable Interfaces as Bone Implant Materials |
| title_short | Magnesium Alloys With Tunable Interfaces as Bone Implant Materials |
| title_sort | magnesium alloys with tunable interfaces as bone implant materials |
| topic | interfacial engineering magnesium alloy surface coating corrosion biomedical application |
| url | https://www.frontiersin.org/article/10.3389/fbioe.2020.00564/full |
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