The diverse influences of relaxin-like peptide family on tumor progression: Potential opportunities and emerging challenges
Relaxin-like peptide family exhibit differential expression patterns in various types of cancers and play a role in cancer development. This family participates in tumorigenic processes encompassing proliferation, migration, invasion, tumor microenvironment, immune microenvironment, and anti-cancer...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-01-01
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| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024004948 |
| _version_ | 1797328641918500864 |
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| author | Jungchan Jung Hyunho Han |
| author_facet | Jungchan Jung Hyunho Han |
| author_sort | Jungchan Jung |
| collection | DOAJ |
| description | Relaxin-like peptide family exhibit differential expression patterns in various types of cancers and play a role in cancer development. This family participates in tumorigenic processes encompassing proliferation, migration, invasion, tumor microenvironment, immune microenvironment, and anti-cancer resistance, ultimately influencing patient prognosis. In this review, we explore the mechanisms underlying the interaction between the RLN-like peptide family and tumors and provide an overview of therapeutic approaches utilizing this interaction. |
| first_indexed | 2024-03-08T06:54:37Z |
| format | Article |
| id | doaj.art-179bd99315464de69f9dc032e7dafed7 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-03-08T06:54:37Z |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-179bd99315464de69f9dc032e7dafed72024-02-03T06:37:34ZengElsevierHeliyon2405-84402024-01-01102e24463The diverse influences of relaxin-like peptide family on tumor progression: Potential opportunities and emerging challengesJungchan Jung0Hyunho Han1Department of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul, 03722, Republic of KoreaCorresponding author.; Department of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul, 03722, Republic of KoreaRelaxin-like peptide family exhibit differential expression patterns in various types of cancers and play a role in cancer development. This family participates in tumorigenic processes encompassing proliferation, migration, invasion, tumor microenvironment, immune microenvironment, and anti-cancer resistance, ultimately influencing patient prognosis. In this review, we explore the mechanisms underlying the interaction between the RLN-like peptide family and tumors and provide an overview of therapeutic approaches utilizing this interaction.http://www.sciencedirect.com/science/article/pii/S2405844024004948RelaxinInsulin-like peptideCancerTMEECM |
| spellingShingle | Jungchan Jung Hyunho Han The diverse influences of relaxin-like peptide family on tumor progression: Potential opportunities and emerging challenges Heliyon Relaxin Insulin-like peptide Cancer TME ECM |
| title | The diverse influences of relaxin-like peptide family on tumor progression: Potential opportunities and emerging challenges |
| title_full | The diverse influences of relaxin-like peptide family on tumor progression: Potential opportunities and emerging challenges |
| title_fullStr | The diverse influences of relaxin-like peptide family on tumor progression: Potential opportunities and emerging challenges |
| title_full_unstemmed | The diverse influences of relaxin-like peptide family on tumor progression: Potential opportunities and emerging challenges |
| title_short | The diverse influences of relaxin-like peptide family on tumor progression: Potential opportunities and emerging challenges |
| title_sort | diverse influences of relaxin like peptide family on tumor progression potential opportunities and emerging challenges |
| topic | Relaxin Insulin-like peptide Cancer TME ECM |
| url | http://www.sciencedirect.com/science/article/pii/S2405844024004948 |
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