Drosophila exercise, an emerging model bridging the fields of exercise and aging in human

Exercise is one of the most effective treatments for the diseases of aging. In recent years, a growing number of researchers have used Drosophila melanogaster to study the broad benefits of regular exercise in aging individuals. With the widespread use of Drosophila exercise models and the upgrading...

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Main Authors: Meng Ding, Hongyu Li, Lan Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.966531/full
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author Meng Ding
Hongyu Li
Lan Zheng
author_facet Meng Ding
Hongyu Li
Lan Zheng
author_sort Meng Ding
collection DOAJ
description Exercise is one of the most effective treatments for the diseases of aging. In recent years, a growing number of researchers have used Drosophila melanogaster to study the broad benefits of regular exercise in aging individuals. With the widespread use of Drosophila exercise models and the upgrading of the Drosophila exercise apparatus, we should carefully examine the differential contribution of regular exercise in the aging process to facilitate more detailed quantitative measurements and assessment of the exercise phenotype. In this paper, we review some of the resources available for Drosophila exercise models. The focus is on the impact of regular exercise or exercise adaptation in the aging process in Drosophila and highlights the great potential and current challenges faced by this model in the field of anti-aging research.
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spelling doaj.art-17a121cfd531432481834dc4227333342022-12-22T03:12:48ZengFrontiers Media S.A.Frontiers in Cell and Developmental Biology2296-634X2022-09-011010.3389/fcell.2022.966531966531Drosophila exercise, an emerging model bridging the fields of exercise and aging in humanMeng DingHongyu LiLan ZhengExercise is one of the most effective treatments for the diseases of aging. In recent years, a growing number of researchers have used Drosophila melanogaster to study the broad benefits of regular exercise in aging individuals. With the widespread use of Drosophila exercise models and the upgrading of the Drosophila exercise apparatus, we should carefully examine the differential contribution of regular exercise in the aging process to facilitate more detailed quantitative measurements and assessment of the exercise phenotype. In this paper, we review some of the resources available for Drosophila exercise models. The focus is on the impact of regular exercise or exercise adaptation in the aging process in Drosophila and highlights the great potential and current challenges faced by this model in the field of anti-aging research.https://www.frontiersin.org/articles/10.3389/fcell.2022.966531/fullDrosophilaexerciseagingobesitycardiac aginglipid metabolism
spellingShingle Meng Ding
Hongyu Li
Lan Zheng
Drosophila exercise, an emerging model bridging the fields of exercise and aging in human
Frontiers in Cell and Developmental Biology
Drosophila
exercise
aging
obesity
cardiac aging
lipid metabolism
title Drosophila exercise, an emerging model bridging the fields of exercise and aging in human
title_full Drosophila exercise, an emerging model bridging the fields of exercise and aging in human
title_fullStr Drosophila exercise, an emerging model bridging the fields of exercise and aging in human
title_full_unstemmed Drosophila exercise, an emerging model bridging the fields of exercise and aging in human
title_short Drosophila exercise, an emerging model bridging the fields of exercise and aging in human
title_sort drosophila exercise an emerging model bridging the fields of exercise and aging in human
topic Drosophila
exercise
aging
obesity
cardiac aging
lipid metabolism
url https://www.frontiersin.org/articles/10.3389/fcell.2022.966531/full
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